Diagnosis and management of cirrhosis and its complications: a review
Importance Cirrhosis affects approximately 2.2 million adults in the US. From 2010 to 2021,
the annual age-adjusted mortality of cirrhosis increased from 14.9 per 100 000 to 21.9 per …
the annual age-adjusted mortality of cirrhosis increased from 14.9 per 100 000 to 21.9 per …
Steatotic liver disease
Steatotic liver disease is the overarching term for conditions characterised by abnormal lipid
accumulation in the liver (liver or hepatic steatosis). Steatotic liver disease encompasses …
accumulation in the liver (liver or hepatic steatosis). Steatotic liver disease encompasses …
[HTML][HTML] Low accuracy of FIB-4 and NAFLD fibrosis scores for screening for liver fibrosis in the population
Background & Aims Fibrosis-4 (FIB-4) and the nonalcoholic fatty liver disease fibrosis score
(NFS) are the 2 most popular noninvasive blood-based serum tests proposed for …
(NFS) are the 2 most popular noninvasive blood-based serum tests proposed for …
AASLD practice guidance on risk stratification and management of portal hypertension and varices in cirrhosis
This Practice Guidance from the American Association for the Study of Liver Disease
(AASLD) intends to coalesce best practice recommendations for the identification of portal …
(AASLD) intends to coalesce best practice recommendations for the identification of portal …
Noninvasive proteomic biomarkers for alcohol-related liver disease
Alcohol-related liver disease (ALD) is a major cause of liver-related death worldwide, yet
understanding of the three key pathological features of the disease—fibrosis, inflammation …
understanding of the three key pathological features of the disease—fibrosis, inflammation …
Using the ELF test, FIB-4 and NAFLD fibrosis score to screen the population for liver disease
M Kjaergaard, KP Lindvig, KH Thorhauge… - Journal of …, 2023 - Elsevier
Background & Aims There is a need for accurate biomarkers of fibrosis for population
screening of alcohol-related and non-alcoholic fatty liver disease (ALD, NAFLD). We …
screening of alcohol-related and non-alcoholic fatty liver disease (ALD, NAFLD). We …
Validation of the new nomenclature of steatotic liver disease in patients with a history of excessive alcohol intake: an analysis of data from a prospective cohort study
Background Steatotic liver disease is a new overarching term that includes metabolic
dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol …
dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol …
[HTML][HTML] Alcohol abstinence improves prognosis across all stages of portal hypertension in alcohol-related cirrhosis
Abstract Background and Aims Alcohol-related liver disease is a leading cause of liver-
related mortality. The effect of alcohol abstinence on the natural history of alcohol-related …
related mortality. The effect of alcohol abstinence on the natural history of alcohol-related …
Hepatic recompensation according to Baveno VII criteria is linked to a significant survival benefit in decompensated alcohol‐related cirrhosis
Abstract Background & Aims Removing the primary aetiological factor in decompensated
cirrhosis may lead to a restoration of hepatic function. In this study, we investigated the …
cirrhosis may lead to a restoration of hepatic function. In this study, we investigated the …
Rifaximin-α for liver fibrosis in patients with alcohol-related liver disease (GALA-RIF): a randomised, double-blind, placebo-controlled, phase 2 trial
Background Alcohol is the leading cause of liver-related mortality worldwide. The gut–liver
axis is considered a key driver in alcohol-related liver disease. Rifaximin-α improves gut …
axis is considered a key driver in alcohol-related liver disease. Rifaximin-α improves gut …