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Native top‐down mass spectrometry for higher‐order structural characterization of proteins and complexes
R Liu, S ** of the spatial
distribution of proteins in biological tissues. We have previously demonstrated imaging of …
distribution of proteins in biological tissues. We have previously demonstrated imaging of …
Advances and emerging medical applications of direct mass spectrometry technologies for tissue analysis
Offering superb speed, chemical specificity, and analytical sensitivity, direct mass
spectrometry (MS) technologies are highly amenable for the molecular analysis of complex …
spectrometry (MS) technologies are highly amenable for the molecular analysis of complex …
Tissue washing improves native ambient mass spectrometry detection of membrane proteins directly from tissue
Native ambient mass spectrometry enables the in situ analysis of proteins and their
complexes directly from tissue, providing both structural and spatial information. Until …
complexes directly from tissue, providing both structural and spatial information. Until …
Mass spectrometry imaging of SOD1 protein-metal complexes in SOD1G93A transgenic mice implicates demetalation with pathology
Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of motor neurons in the
central nervous system (CNS). Mutations in the metalloenzyme SOD1 are associated with …
central nervous system (CNS). Mutations in the metalloenzyme SOD1 are associated with …
Expanding Spatial Metabolomics Coverage with Lithium-Doped Nanospray Desorption Electrospray Ionization Mass Spectrometry Imaging
K Nguyen, G Carleton, JJ Lum, KD Duncan - Analytical Chemistry, 2024 - ACS Publications
Spatial metabolomics has emerged as a powerful tool capable of revealing metabolic
gradients throughout complex heterogeneous tissues. While mass spectrometry imaging …
gradients throughout complex heterogeneous tissues. While mass spectrometry imaging …
Nanospray Desorption Electrospray Ionization Mass Spectrometry Imaging (nano-DESI MSI): A Tutorial Review
M Iqfath, SN Wali, S Amer, E Hernly… - ACS Measurement …, 2024 - ACS Publications
Nanospray desorption electrospray ionization (nano-DESI) is a liquid-based ambient mass
spectrometry imaging (MSI) technique that enables visualization of analyte distributions in …
spectrometry imaging (MSI) technique that enables visualization of analyte distributions in …
Laser capture microdissection and native mass spectrometry for spatially-resolved analysis of intact protein assemblies in tissue
Previously, we have shown that native ambient mass spectrometry imaging allows the
spatial map** of folded proteins and their complexes in thin tissue sections. Subsequent …
spatial map** of folded proteins and their complexes in thin tissue sections. Subsequent …
Emerging native Orbitrap mass spectrometry for probing higher-order structures of proteins: Recent progress and applications
L Li, Y Zhang, Y Lv, F Qu, Q Ma - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Native mass spectrometry (MS) is a powerful and complementary tool and has been widely
used for the characterization of proteins and protein complexes. Over the past decades …
used for the characterization of proteins and protein complexes. Over the past decades …