Platelets play significant and varied roles in cancer progression, as detailed throughout this
review series, via direct interactions with cancer cells and by long-range indirect interactions …

The high occurrence of cancer-associated thrombosis is associated with elevated thrombin
generation. Tumour cells increase the potential for thrombin generation both directly …

Background: In 2001, we studied the presence and coagulant properties of “microparticles”
in the blood of healthy humans. Since then, multiple improvements in detection, isolation …

Background Metastasis is the main cause of death in patients with colorectal cancer (CRC).
Apart from platelets, platelet-derived microparticles (PMPs) are also considered important …

Predicting survival accurately in patients with advanced cancer is important in guiding
interventions and planning future care. Objective tools are therefore needed. Blood …

An increasing number of studies show that platelets as well as platelet-derived
microparticles (PMP) play significant roles in cancer malignancy and disease progression …

Platelet-derived microparticles (PMPs) have long been known to increase in circulation in
the presence of cancer, and have been considered to be cancer promoting by multiple …

During hemostasis, thrombosis, and inflammation, activated blood platelets release
extracellular vesicles (PEVs) that represent biological mediators of physiological and …

Platelets have been extensively implicated in the progression of cancer and platelet-derived
extracellular vesicles (PEVs) are gaining growing attention as potential mediators of the …

Background: Platelets can support cancer progression via the release of microparticles and
microvesicles that enhance the migratory behaviour of recipient cancer cells. We recently …