Cell kinetic approaches to the search for anti-aging drugs: Thirty years after
AN Khokhlov - Moscow University Biological Sciences Bulletin, 2018 - Springer
This is a brief overview of the ideas of the possibility of using the cell kinetic model
developed by the author in the 1980s to test, in experiments on cell cultures, potential …
developed by the author in the 1980s to test, in experiments on cell cultures, potential …
NANOG attenuates hair follicle‐derived mesenchymal stem cell senescence by upregulating PBX1 and activating AKT signaling
F Liu, J Shi, Y Zhang, A Lian, X Han… - Oxidative medicine …, 2019 - Wiley Online Library
Stem cells derived from elderly donors or harvested by repeated subculture exhibit a marked
decrease in proliferative capacity and multipotency, which not only compromises their …
decrease in proliferative capacity and multipotency, which not only compromises their …
Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides
V Ashapkin, V Khavinson, G Shilovsky… - Molecular Biology …, 2020 - Springer
Abstract Effects of the short peptides Ala-Glu-Asp (AED), Lys-Glu-Asp (KED) and Lys-Glu
(KE) on the expression of IGF1, FOXO1, TERT, TNKS2, and NFκB genes were studied in …
(KE) on the expression of IGF1, FOXO1, TERT, TNKS2, and NFκB genes were studied in …
[HTML][HTML] Poly (ADP-Ribosyl) Code Functions
NV Maluchenko, DO Koshkina, AV Feofanov… - Acta …, 2021 - ncbi.nlm.nih.gov
Poly (ADP-ribosyl) ation plays a key role in cellular metabolism. Covalent poly (ADP-ribosyl)
ation affects the activity of the proteins engaged in DNA repair, chromatin structure …
ation affects the activity of the proteins engaged in DNA repair, chromatin structure …
Evolution of Longevity in Tetrapods: Safety Is More Important than Metabolism Level
Various environmental morphological and behavioral factors can determine the longevity of
representatives of various taxa. Long-lived species develop systems aimed at increasing …
representatives of various taxa. Long-lived species develop systems aimed at increasing …
Calculating Aging: Analysis of Survival Curves in the Norm and Pathology, Fluctuations in Mortality Dynamics, Characteristics of Lifespan Distribution, and Indicators …
GA Shilovsky - Biochemistry (Moscow), 2024 - Springer
The article describes the history of studies of survival data carried out at the Research
Institute of Physico-Chemical Biology under the leadership of Academician VP Skulachev …
Institute of Physico-Chemical Biology under the leadership of Academician VP Skulachev …
Influence of AMPK on the Functioning of the Circadian Clock and Its Possible Role in the Development of Age-Related Metabolic Disorders
Circadian rhythms ensure the synchronization of the physiology of cells and tissues in
accordance with daily changes in the environment. These rhythms are maintained by …
accordance with daily changes in the environment. These rhythms are maintained by …
EVOLUTION OF LONGEVITY IN TETRAPODA: SAFETY IS MORE IMPORTANT THAN METABOLISM LEVEL
Various environmental morphological and behavioral factors may be decisive in the
longevity of representatives of various taxa. Long-lived species develop systems aimed at …
longevity of representatives of various taxa. Long-lived species develop systems aimed at …
Poly (ADP-Ribosyl) Code Functions
НВ Малюченко, ДО Кошкина, АВ Феофанов… - Acta Naturae …, 2021 - elibrary.ru
Поли (АDP-рибозил) ирование играет важнейшую роль в клеточном метаболизме.
Ковалентное поли (АDP-рибозил) ирование влияет на работу белков, вовлеченных в …
Ковалентное поли (АDP-рибозил) ирование влияет на работу белков, вовлеченных в …
CALCULATION OF AGING: ANALYSIS OF SURVIVAL CURVES IN NORMAL AND IN PATHOLOGY, FLUCTUATIONS IN MORTALITY DYNAMICS …
GA Shilovsky - Biohimiâ, 2024 - journals.rcsi.science
The article describes the history of studies of survival data carried out at the Research
Institute of Physico-Chemical Biology under the leadership of Academician VP Skulachev …
Institute of Physico-Chemical Biology under the leadership of Academician VP Skulachev …