The intriguing mitoNEET: functional and spectroscopic properties of a unique [2Fe-2S] cluster coordination geometry
Despite the number of cellular and pathological mitoNEET-related processes, very few
details are known about the mechanism of action of the protein. The recently discovered …
details are known about the mechanism of action of the protein. The recently discovered …
[HTML][HTML] Aqueous stability and redox chemistry of synthetic [Fe4S4] clusters
V Waser, TR Ward - Coordination Chemistry Reviews, 2023 - Elsevier
Iron-sulfur proteins are ubiquitous in nature, acting as electron carriers and catalysts. Hence,
a plethora of synthetic analogs has been prepared to serve as active site models. However …
a plethora of synthetic analogs has been prepared to serve as active site models. However …
Relaxation-based NMR assignment: Spotlights on ligand binding sites in human CISD3
CISD3 is a mitochondrial protein belonging to the NEET proteins family, bearing two [Fe 2 S
2] clusters coordinated by CDGSH domains. At variance with the other proteins of the NEET …
2] clusters coordinated by CDGSH domains. At variance with the other proteins of the NEET …
Paramagnetic nuclear magnetic resonance: The Toolkit
Nuclear Magnetic Resonance (NMR) spectroscopy is the ideal tool to address the structure,
reactivity and dynamics of both inorganic and biological substances. The knowledge of …
reactivity and dynamics of both inorganic and biological substances. The knowledge of …
NMR of Paramagnetic Proteins: 13C Derived Paramagnetic Relaxation Enhancements Are an Additional Source of Structural Information in Solution
In paramagnetic metalloproteins, longitudinal relaxation rates of 13C′ and 13Cα nuclei can
be measured using 13C detected experiments and converted into electron spin-nuclear spin …
be measured using 13C detected experiments and converted into electron spin-nuclear spin …
Electron transfer in biological systems
HM Marques - JBIC Journal of Biological Inorganic Chemistry, 2024 - Springer
Examples of how metalloproteins feature in electron transfer processes in biological systems
are reviewed. Attention is focused on the electron transport chains of cellular respiration and …
are reviewed. Attention is focused on the electron transport chains of cellular respiration and …
[HTML][HTML] Regulations of mitoNEET by the key redox homeostasis molecule glutathione
C Mons, M Salameh, T Botzanowski… - Journal of Inorganic …, 2024 - Elsevier
Human mitoNEET (mNT) and CISD2 are two NEET proteins characterized by an atypical
[2Fe-2S] cluster coordination involving three cysteines and one histidine. They act as redox …
[2Fe-2S] cluster coordination involving three cysteines and one histidine. They act as redox …
1H, 13C and 15N assignment of the human mitochondrial paramagnetic iron–sulfur protein CISD3
CISD3 is a mitochondrial protein that contains two [2Fe–2S] clusters. This protein is
overexpressed in some types of cancer, so it has emerged as a potential drug target. A …
overexpressed in some types of cancer, so it has emerged as a potential drug target. A …
Fast 2D NMR to Investigate Dynamic Events in Biomolecules
Biological macromolecules (proteins, nucleic acids and polysaccharides) are highly
complex in terms of not only their structure but also dynamical and kinetic properties …
complex in terms of not only their structure but also dynamical and kinetic properties …