• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Hypertension is a global health problem, with> 1.3 billion individuals with high blood
pressure worldwide. In this Review, we present an inflammatory paradigm for hypertension …

Endothelium plays a fundamental role in the cardiovascular system, forming an interface
between blood and adjacent tissues by regulating the vascular tone through the synthesis of …

Maintenance of endothelial cell integrity is an important component of human health and
disease since the endothelium can perform various functions including regulation of …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

Cardiovascular autonomic dysfunction (CVAD) is a malfunction of the cardiovascular system
caused by deranged autonomic control of circulatory homeostasis. CVAD is an important …

In the last two decades evidence has gradually accumulated suggesting that the eye may be
a unique window for cardiovascular risk stratification based on the assessment of subclinical …

Hypertension remains the main cause of cardiovascular complications leading to increased
mortality. The discoveries of recent years underline the important role of endothelial …

The vascular endothelium is a multifunctional cellular system which directly influences blood
components and cells within the vessel wall in a given tissue. Importantly, this cellular …

Aims Endothelial function is essential for cardiovascular health, and flow-mediated dilation
(FMD) is an established technique to measure it. This paper aims to assess FMD values in …