Conventional chemotherapy lacking target selectivity often leads to severe side effects,
limiting the effectiveness of chemotherapy. Therefore, drug delivery systems ensuring both …

Nanoparticles have emerged as promising drug delivery systems for the treatment of several
diseases. Novel cancer therapies have exploited these particles as alternative adjuvant …

Peptides are at the cutting edge of contemporary research for new potent, selective, and
safe therapeutical agents. Their rise has reshaped the pharmaceutical landscape, providing …

Peptides are increasingly being developed for use as therapeutics to treat many ailments,
including cancer. Therapeutic peptides have the advantages of target specificity and low …

Hyperbranched polymers (HBPs) have found use in a wide range of applications, such as
optical, electronic and magnetic materials, coatings, additives, supramolecular chemistry …

Receptor-targeting peptides have been extensively pursued for improving binding specificity
and effective accumulation of drugs at the site of interest, and have remained challenging for …

Programmed cell death-ligand 1 (PD-L1) small interfering RNA (siRNA) achieves tumor
immunotherapy by restoring the immune response of T cells, but the efficacy of PD-1/PD-L1 …

Multidrug resistance (MDR) is one of the key barriers in chemotherapy, leading to the
generation of insensitive cancer cells towards administered therapy. Genetic and epigenetic …

Epidermal growth factor receptor (EGFR) is an integral surface protein mediating cellular
response to a number of growth factors. Its overexpression and increased activation due to …

Although the development of effective viral vectors put gene therapy on the road to
commercialization, nonviral vectors show promise for practical use because of their relative …