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Chemical approaches to optimize the properties of organic fluorophores for imaging and sensing
G Jiang, H Liu, H Liu, G Ke, TB Ren… - Angewandte …, 2024 - Wiley Online Library
Organic fluorophores are indispensable tools in cells, tissue and in vivo imaging, and have
enabled much progress in the wide range of biological and biomedical fields. However …
enabled much progress in the wide range of biological and biomedical fields. However …
Molecular imaging and disease theranostics with renal-clearable optical agents
Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …
resolution and the availability of numerous optical agents. However, many optical imaging …
Near-infrared fluorophores for biomedical imaging
In vivo near-infrared (NIR) fluorescence imaging is an emerging biomedical imaging
modality for use in both fundamental scientific research and clinical practice. Owing to …
modality for use in both fundamental scientific research and clinical practice. Owing to …
Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
The pursuit of polymethine fluorophores with NIR-II emission and high brightness for in vivo applications
Polymethine cyanine dyes, as the most important class of organic near-infrared-II (NIR-II)
fluorophores, recently received increasing attention due to their high molar extinction …
fluorophores, recently received increasing attention due to their high molar extinction …
Doubly Strapped Zwitterionic NIR‐I and NIR‐II Heptamethine Cyanine Dyes for Bioconjugation and Fluorescence Imaging
Heptamethine cyanine dyes enable deep tissue fluorescence imaging in the near infrared
(NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1 have been tested …
(NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1 have been tested …
A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging
Fluorescence imaging in the second near-infrared window (NIR-II) allows visualization of
deep anatomical features with an unprecedented degree of clarity. NIR-II fluorophores draw …
deep anatomical features with an unprecedented degree of clarity. NIR-II fluorophores draw …
Bright Chromenylium Polymethine Dyes Enable Fast, Four-Color In Vivo Imaging with Shortwave Infrared Detection
Optical imaging within the shortwave infrared (SWIR, 1000–2000 nm) region of the
electromagnetic spectrum has enabled high-resolution and high-contrast imaging in mice …
electromagnetic spectrum has enabled high-resolution and high-contrast imaging in mice …
Clearance pathways and tumor targeting of imaging nanoparticles
M Yu, J Zheng - ACS nano, 2015 - ACS Publications
A basic understanding of how imaging nanoparticles are removed from the normal
organs/tissues but retained in the tumors is important for their future clinical applications in …
organs/tissues but retained in the tumors is important for their future clinical applications in …
Beyond the margins: real-time detection of cancer using targeted fluorophores
RR Zhang, AB Schroeder, JJ Grudzinski… - Nature reviews Clinical …, 2017 - nature.com
Over the past two decades, synergistic innovations in imaging technology have resulted in a
revolution in which a range of biomedical applications are now benefiting from fluorescence …
revolution in which a range of biomedical applications are now benefiting from fluorescence …