The critical role of the branched chain amino acids (BCAAs) catabolism-regulating enzymes, branched-chain aminotransferase (BCAT) and branched-chain α-keto …

A Dimou, V Tsimihodimos, E Bairaktari - International Journal of …, 2022 - mdpi.com
Branched chain amino acids (BCAAs), leucine, isoleucine and valine, are essential amino
acids widely studied for their crucial role in the regulation of protein synthesis mainly through …

Obesity in type 1 diabetes: pathophysiology, clinical impact, and mechanisms

KD Corbin, KA Driscoll, RE Pratley, SR Smith… - Endocrine …, 2018 - academic.oup.com
There has been an alarming increase in the prevalence of obesity in people with type 1
diabetes in recent years. Although obesity has long been recognized as a major risk factor …

Resistance versus aerobic exercise: acute effects on glycemia in type 1 diabetes

JE Yardley, GP Kenny, BA Perkins, MC Riddell… - Diabetes …, 2013 - diabetesjournals.org
OBJECTIVE In type 1 diabetes, small studies have found that resistance exercise (weight
lifting) reduces HbA1c. In the current study, we examined the acute impacts of resistance …

Autophagy and mitochondria in obesity and type 2 diabetes

J Sarparanta, M Garcia-Macia… - Current diabetes …, 2017 - benthamdirect.com
Introduction: Obesity and type 2 diabetes are growing health problems worldwide. The three
principal diabetogenic factors are adiposity, insulin resistance in skeletal muscle, and …

[HTML][HTML] Youth with type 1 diabetes mellitus are more inactive and sedentary than apparently healthy peers: a systematic review and meta-analysis

N Huerta-Uribe, IA Hormazábal-Aguayo… - Diabetes research and …, 2023 - Elsevier
Aims To conduct a meta-analysis of differences in physical activity, sedentary behaviour,
and physical fitness between children and adolescents with type 1 diabetes and their …

Role of impaired glycolysis in perturbations of amino acid metabolism in diabetes mellitus

M Holeček - International Journal of Molecular Sciences, 2023 - mdpi.com
The most frequent alterations in plasma amino acid concentrations in type 1 and type 2
diabetes are decreased L-serine and increased branched-chain amino acid (BCAA; valine …

[HTML][HTML] Adiponectin—Consideration for its role in skeletal muscle health

MP Krause, KJ Milne, TJ Hawke - International journal of molecular …, 2019 - mdpi.com
Adiponectin regulates metabolism through blood glucose control and fatty acid oxidation,
partly mediated by downstream effects of adiponectin signaling in skeletal muscle. More …

Sarcopenia and frailty in older patients with diabetes mellitus

H Umegaki - Geriatrics & gerontology international, 2016 - Wiley Online Library
Sarcopenia is defined as age‐associated loss of muscle mass and function, and is
frequently accompanied by diabetes mellitus (DM) in older adults. Some of the mechanisms …

Advanced glycation end‐products induce skeletal muscle atrophy and dysfunction in diabetic mice via a RAGE‐mediated, AMPK‐down‐regulated, Akt pathway

CY Chiu, RS Yang, ML Sheu, DC Chan… - The Journal of …, 2016 - Wiley Online Library
Diabetic myopathy, a less studied complication of diabetes, exhibits the clinical observations
characterized by a less muscle mass, muscle weakness and a reduced physical functional …

[PDF][PDF] Exercise and type 1 diabetes (T1DM)

P Galassetti, MC Riddell - Compr Physiol, 2013 - paulogentil.com
Physical exercise is firmly incorporated in the management of type 1 diabetes (T1DM), due
to multiple recognized beneficial health effects (cardiovascular disease prevention being …