Biology, vulnerabilities and clinical applications of circulating tumour cells
In recent years, exceptional technological advances have enabled the identification and
interrogation of rare circulating tumour cells (CTCs) from blood samples of patients, leading …
interrogation of rare circulating tumour cells (CTCs) from blood samples of patients, leading …
Molecular analysis of circulating tumour cells—biology and biomarkers
MG Krebs, RL Metcalf, L Carter, G Brady… - Nature reviews Clinical …, 2014 - nature.com
Growing evidence for intratumour heterogeneity informs us that single-site biopsies fall short
of revealing the complete genomic landscape of a tumour. With an expanding repertoire of …
of revealing the complete genomic landscape of a tumour. With an expanding repertoire of …
A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis
Z Yu, P Zhou, W Pan, N Li, B Tang - Nature Communications, 2018 - nature.com
Photodynamic therapy (PDT) is ineffective against deeply seated metastatic tumors due to
poor penetration of the excitation light. Herein, we developed a biomimetic nanoreactor (bio …
poor penetration of the excitation light. Herein, we developed a biomimetic nanoreactor (bio …
Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors.
H Sun, J Su, Q Meng, Q Yin, L Chen, W Gu… - … (Deerfield Beach, Fla …, 2016 - europepmc.org
A unique biomimetic drug-delivery system composed of 4T1-breast-cancer-cell membranes
and paclitaxel-loaded polymeric nanoparticles (PPNs)(cell-membrane-coated PPNs) …
and paclitaxel-loaded polymeric nanoparticles (PPNs)(cell-membrane-coated PPNs) …
Cell membrane-coated nanosized active targeted drug delivery systems homing to tumor cells: A review
Z He, Y Zhang, N Feng - Materials Science and Engineering: C, 2020 - Elsevier
Cancer is a leading cause of mortality worldwide. Cell membrane-coated nanocarriers
actively targeting tumor sites are known to circumvent the limitations of conventional …
actively targeting tumor sites are known to circumvent the limitations of conventional …
Circulating tumor cells: from new biological insights to clinical practice
X Gu, S Wei, X Lv - Signal Transduction and Targeted Therapy, 2024 - nature.com
The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …
tumor cells migrate through the bloodstream from the original site to other parts of the body …
Biomimetic cell-derived nanocarriers in cancer research
Nanoparticles have now long demonstrated capabilities that make them attractive to use in
biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or …
biology and medicine. Some of them, such as lipid nanoparticles (SARS-CoV-2 vaccines) or …
Altered tumor-cell glycosylation promotes metastasis
I Häuselmann, L Borsig - Frontiers in oncology, 2014 - frontiersin.org
Malignant transformation of cells is associated with aberrant glycosylation presented on the
cell-surface. Commonly observed changes in glycan structures during malignancy …
cell-surface. Commonly observed changes in glycan structures during malignancy …
[HTML][HTML] Circulating tumor cell clusters: What we know and what we expect
Y Hong, F Fang, Q Zhang - … journal of oncology, 2016 - spandidos-publications.com
The major cause of cancer-associated mortality is tumor metastasis, a disease that is far
from understood. Many studies have observed circulating tumor cells (CTCs) in patients' …
from understood. Many studies have observed circulating tumor cells (CTCs) in patients' …
Galectin-3–a jack-of-all-trades in cancer
Galectin-3 is a mammalian β-galactoside-binding protein that is expressed by various types
of human cells. Changes in galectin-3 expression and subcellular and intercellular …
of human cells. Changes in galectin-3 expression and subcellular and intercellular …