The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Data analysis is a very challenging task in LC-MS metabolomic studies. The use of powerful
analytical techniques (eg, high-resolution mass spectrometry) provides high-dimensional …

Gas chromatography–mass spectrometry (GC‐MS)–based metabolomics is ideal for
identifying and quantitating small‐molecule metabolites (< 650 Da), including small acids …

Exercise has a wide range of systemic effects. In animal models, repeated exertion reduces
malignant tumor progression, and clinically, exercise can improve outcome for cancer …

Mass spectrometry (MS) and nuclear magnetic resonance (NMR) have evolved as the most
common techniques in metabolomics studies, and each brings its own advantages and …

Metabolism has an essential role in biological systems. Identification and quantitation of the
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …

Continuing improvements in analytical technology along with an increased interest in
performing comprehensive, quantitative metabolic profiling, is leading to increased interest …

The ability of a chromatographic method to successful separate, identify and quantitate
species is determined by many factors, many of which are in the control of the experimenter …

Metabolomics studies generate increasingly complex data tables, which are hard to
summarize and visualize without appropriate tools. The use of chemometrics tools, eg …

Non-targeted metabolomics is the hypothesis generating, global unbiased analysis of all the
small-molecule metabolites present within a biological system, under a given set of …