Zebrafish pancreas development

N Tiso, E Moro, F Argenton - Molecular and cellular endocrinology, 2009‏ - Elsevier
An accurate understanding of the molecular events governing pancreas development can
have an impact on clinical medicine related to diabetes, obesity and pancreatic cancer …

Transcriptional and epigenetic mechanisms of early cortical development: An examination of how Pax6 coordinates cortical development

AR Ypsilanti, JLR Rubenstein - Journal of Comparative …, 2016‏ - Wiley Online Library
The development of the cortex is an elaborate process that integrates a plethora of finely
tuned molecular processes ranging from carefully regulated gradients of transcription …

[HTML][HTML] Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon

B Adolf, P Chapouton, CS Lam, S Topp… - Developmental …, 2006‏ - Elsevier
Our understanding of the cellular and molecular mechanisms underlying the adult neural
stem cell state remains fragmentary. To provide new models on this issue, we searched for …

Dynamics of enhancer chromatin signatures mark the transition from pluripotency to cell specification during embryogenesis

O Bogdanović, A Fernandez-Miñán, JJ Tena… - Genome …, 2012‏ - genome.cshlp.org
The generation of distinctive cell types that form different tissues and organs requires
precise, temporal and spatial control of gene expression. This depends on specific cis …

A direct role for Sox10 in specification of neural crest-derived sensory neurons

TJ Carney, KA Dutton, E Greenhill, M Delfino-Machín… - 2006‏ - journals.biologists.com
sox10 is necessary for development of neural and pigment cell derivatives of the neural
crest (NC). However, whereas a direct role for Sox10 activity has been established in …

Oxidative stress induced by hydrogen peroxide disrupts zebrafish visual development by altering apoptosis, antioxidant and estrogen related genes

F Saputra, M Kishida, SY Hu - Scientific Reports, 2024‏ - nature.com
Hydrogen peroxide is considered deleterious molecule that cause cellular damage integrity
and function. Its key redox signaling molecule in oxidative stress and exerts toxicity on a …

Epigenetic CpG demethylation of the promoter and reactivation of the expression of Neurog1 by curcumin in prostate LNCaP cells

L Shu, TO Khor, JH Lee, SSS Boyanapalli, Y Huang… - The AAPS journal, 2011‏ - Springer
Curcumin (CUR), a major bioactive polyphenolic component from turmeric curry, Curcuma
longa, has been shown to be a potent anti-cancer phytochemical with well-established anti …

Chromatin accessibility established by Pou5f3, Sox19b and Nanog primes genes for activity during zebrafish genome activation

M Pálfy, G Schulze, E Valen, NL Vastenhouw - PLoS Genetics, 2020‏ - journals.plos.org
In many organisms, early embryonic development is driven by maternally provided factors
until the controlled onset of transcription during zygotic genome activation. The regulation of …

Characterization of Müller glia and neuronal progenitors during adult zebrafish retinal regeneration

R Thummel, SC Kassen, JM Enright, CM Nelson… - Experimental eye …, 2008‏ - Elsevier
The adult zebrafish retina exhibits a robust regenerative response following light-induced
photoreceptor cell death. This response is initiated by the Müller glia proliferating in the …

Gene expression changes in develo** zebrafish as potential markers for rapid developmental neurotoxicity screening

CY Fan, J Cowden, SO Simmons, S Padilla… - Neurotoxicology and …, 2010‏ - Elsevier
Hazard information essential to guide developmental neurotoxicity risk assessments is
limited for many chemicals. As developmental neurotoxicity testing using rodents is …