Mitochondrial metabolic signatures in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death worldwide.
HCC progression and metastasis are closely related to altered mitochondrial metabolism …
HCC progression and metastasis are closely related to altered mitochondrial metabolism …
The metabolic fates of pyruvate in normal and neoplastic cells
Pyruvate occupies a central metabolic node by virtue of its position at the crossroads of
glycolysis and the tricarboxylic acid (TCA) cycle and its production and fate being governed …
glycolysis and the tricarboxylic acid (TCA) cycle and its production and fate being governed …
HBXIP drives metabolic reprogramming in hepatocellular carcinoma cells via METTL3‐mediated m6A modification of HIF‐1α
N Yang, T Wang, Q Li, F Han, Z Wang… - Journal of Cellular …, 2021 - Wiley Online Library
Cancer cells sustain high levels of glycolysis and glutaminolysis via reprogramming of
intracellular metabolism, which represents a driver of hepatocellular carcinoma (HCC) …
intracellular metabolism, which represents a driver of hepatocellular carcinoma (HCC) …
Construction of a lipid metabolism‐related and immune‐associated prognostic signature for hepatocellular carcinoma
B Hu, XB Yang, XT Sang - Cancer medicine, 2020 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) is one of the most lethal malignancies. We
aimed to identify a robust lipid metabolism‐related signature associated with the HCC …
aimed to identify a robust lipid metabolism‐related signature associated with the HCC …
Glucocorticoid receptor modulates myeloid-derived suppressor cell function via mitochondrial metabolism in immune thrombocytopenia
Y Hou, J **e, S Wang, D Li, L Wang, H Wang… - Cellular & molecular …, 2022 - nature.com
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature
cells and natural inhibitors of adaptive immunity. Intracellular metabolic changes in MDSCs …
cells and natural inhibitors of adaptive immunity. Intracellular metabolic changes in MDSCs …
Hsa‑circRNA‑G004213 promotes cisplatin sensitivity by regulating miR‑513b‑5p/PRPF39 in liver cancer Corrigendum in/10.3892/mmr. 2021.12359
L Qin, Z Zhan, C Wei, X Li… - Molecular medicine …, 2021 - spandidos-publications.com
In recent years, increasing evidence has confirmed that exosomal circular RNAs (circRNAs)
serve a crucial role in the prognostic prediction and diagnosis of liver cancer (LC). The …
serve a crucial role in the prognostic prediction and diagnosis of liver cancer (LC). The …
Alterations of the gut microbiome and fecal metabolome in colorectal cancer: implication of intestinal metabolism for tumorigenesis
X Du, Q Li, Z Tang, L Yan, L Zhang, Q Zheng… - Frontiers in …, 2022 - frontiersin.org
Objective: The gut microbiota and its metabolites are important for host physiological
homeostasis, while dysbiosis is related to diseases including the development of cancers …
homeostasis, while dysbiosis is related to diseases including the development of cancers …
[HTML][HTML] Deletion of lactate dehydrogenase-a impairs oncogene-induced mouse hepatocellular carcinoma development
Abstract Background and Aims Hepatocellular carcinoma (HCC) is a multistep process
whereby abnormally proliferating cancer cells undergo extensive metabolic reprogramming …
whereby abnormally proliferating cancer cells undergo extensive metabolic reprogramming …
β-Catenin mutations as determinants of hepatoblastoma phenotypes in mice
Hepatoblastoma (HB) is the most common pediatric liver cancer. Although long-term survival
of HB is generally favorable, it depends on clinical stage, tumor histology, and a variety of …
of HB is generally favorable, it depends on clinical stage, tumor histology, and a variety of …
[HTML][HTML] Coordinated cross-talk between the myc and mlx networks in liver regeneration and neoplasia
Background & Aims The c-Myc (Myc) Basic helix-loop-helix leucine zipper (bHLH-ZIP)
transcription factor is deregulated in most cancers. In association with Max, Myc controls …
transcription factor is deregulated in most cancers. In association with Max, Myc controls …