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Anaesthesiologists and non-anaesthesiologist sedationists have a limited set of available iv
hypnotics, further reduced by the withdrawal of thiopental in the USA and its near …

The drug-induced, reversible coma of anaesthesia requires three clinical outcomes:
unconsciousness, immobility, and the control of autonomic nervous system (ANS) responses …

Obstructive sleep apnea syndrome (OSAS) is a common sleep related breathing disorder. Its
prevalence is estimated to be between 2% and 25% in the general population. However, the …

Background Non-pharmacological behavioural adjuncts have been suggested as efficient
safe means in reducing discomfort and adverse effects during medical procedures. We …

Objectives. To perform a systematic investigation of medications associated with adverse
sedation events in pediatric patients using critical incident analysis of case reports. Methods …

The tumescent technique for local anesthesia improves the safety of large-volume
liposuction (≥ 1500 ml of fat) by virtually eliminating surgical blood loss and by completely …

The concurrent use of opioids, benzodiazepines (BZDs), and/or alcohol poses a formidable
challenge for clinicians who manage chronic pain. While the escalating use of opioid …

Midazolam is a familiar agent commonly used in the emergency department to provide
sedation prior to procedures such as laceration repair and reduction of dislocations …

Sedation and analgesia are considered by many gas-troenterologists to be an integral
component of the endoscopic examination. For example, more than 98% of endoscopists in …