Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy
H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …
PI3K/Akt/mTOR signaling pathway in cancer stem cells
Cancer stem cells (CSCs) as a small subpopulation in tumor bulk are believed to initiate
tumor formation and are responsible for the resistance to cancer therapy. The proliferation …
tumor formation and are responsible for the resistance to cancer therapy. The proliferation …
Cancer stem cells: A review from origin to therapeutic implications
Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are elucidated as
cells that can perpetuate themselves via autorestoration. These cells are highly resistant to …
cells that can perpetuate themselves via autorestoration. These cells are highly resistant to …
[HTML][HTML] Targeting hypoxia-inducible factor-1alpha: A new strategy for triple-negative breast cancer therapy
Q Liu, C Guan, C Liu, H Li, J Wu, C Sun - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is highly aggressive
and hypoxic compared with other subtypes. The role of hypoxia inducible factor 1α (HIF-1α) …
and hypoxic compared with other subtypes. The role of hypoxia inducible factor 1α (HIF-1α) …
Recent development of aptamer conjugated chitosan nanoparticles as cancer therapeutics
There is a surge in demand for safe and targeted therapy against cancer as the conventional
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …
Colibactin-producing Escherichia coli enhance resistance to chemotherapeutic drugs by promoting epithelial to mesenchymal transition and cancer stem cell …
G Dalmasso, A Cougnoux, T Faïs, V Bonnin… - Gut …, 2024 - Taylor & Francis
Human colorectal cancers (CRCs) are readily colonized by colibactin-producing E. coli
(CoPEC). CoPEC induces DNA double-strand breaks, DNA mutations, genomic instability …
(CoPEC). CoPEC induces DNA double-strand breaks, DNA mutations, genomic instability …
Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) metastasizes to distant organs, which is the
primary cause of mortality; however, specific features mediating organ-specific metastasis …
primary cause of mortality; however, specific features mediating organ-specific metastasis …
CD133 in breast cancer cells: more than a stem cell marker
F Brugnoli, S Grassilli, Y Al-Qassab… - Journal of …, 2019 - Wiley Online Library
Initially correlated with hematopoietic precursors, the surface expression of CD133 was also
found in epithelial and nonepithelial cells from adult tissues in which it has been associated …
found in epithelial and nonepithelial cells from adult tissues in which it has been associated …
Emerging roles of prominin-1 (CD133) in the dynamics of plasma membrane architecture and cell signaling pathways in health and disease
Abstract Prominin-1 (CD133) is a cholesterol-binding membrane glycoprotein selectively
associated with highly curved and prominent membrane structures. It is widely recognized …
associated with highly curved and prominent membrane structures. It is widely recognized …
Mechanisms of melanoma progression and treatment resistance: Role of cancer stem-like cells
Y Al Hmada, RT Brodell, N Kharouf, TW Flanagan… - Cancers, 2024 - mdpi.com
Simple Summary Melanoma is the third most common type of skin cancer. Melanoma is a
heterogeneous tumor, composed of genetically divergent subpopulations. These …
heterogeneous tumor, composed of genetically divergent subpopulations. These …