Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy

H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

PI3K/Akt/mTOR signaling pathway in cancer stem cells

M Ebrahimi, E Nourbakhsh, AZ Hazara… - … -Research and Practice, 2022 - Elsevier
Cancer stem cells (CSCs) as a small subpopulation in tumor bulk are believed to initiate
tumor formation and are responsible for the resistance to cancer therapy. The proliferation …

Cancer stem cells: A review from origin to therapeutic implications

MR Atashzar, R Baharlou, J Karami… - Journal of cellular …, 2020 - Wiley Online Library
Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are elucidated as
cells that can perpetuate themselves via autorestoration. These cells are highly resistant to …

[HTML][HTML] Targeting hypoxia-inducible factor-1alpha: A new strategy for triple-negative breast cancer therapy

Q Liu, C Guan, C Liu, H Li, J Wu, C Sun - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is highly aggressive
and hypoxic compared with other subtypes. The role of hypoxia inducible factor 1α (HIF-1α) …

Recent development of aptamer conjugated chitosan nanoparticles as cancer therapeutics

A Sheikh, S Md, NA Alhakamy, P Kesharwani - International journal of …, 2022 - Elsevier
There is a surge in demand for safe and targeted therapy against cancer as the conventional
treatment approach fails to reach the specific site. Chemotherapeutic agents are generally …

Colibactin-producing Escherichia coli enhance resistance to chemotherapeutic drugs by promoting epithelial to mesenchymal transition and cancer stem cell …

G Dalmasso, A Cougnoux, T Faïs, V Bonnin… - Gut …, 2024 - Taylor & Francis
Human colorectal cancers (CRCs) are readily colonized by colibactin-producing E. coli
(CoPEC). CoPEC induces DNA double-strand breaks, DNA mutations, genomic instability …

Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma

RK Nimmakayala, F Leon, S Rachagani, S Rauth… - Oncogene, 2021 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) metastasizes to distant organs, which is the
primary cause of mortality; however, specific features mediating organ-specific metastasis …

CD133 in breast cancer cells: more than a stem cell marker

F Brugnoli, S Grassilli, Y Al-Qassab… - Journal of …, 2019 - Wiley Online Library
Initially correlated with hematopoietic precursors, the surface expression of CD133 was also
found in epithelial and nonepithelial cells from adult tissues in which it has been associated …

Emerging roles of prominin-1 (CD133) in the dynamics of plasma membrane architecture and cell signaling pathways in health and disease

P Pleskač, CA Fargeas, R Veselska, D Corbeil… - Cellular & Molecular …, 2024 - Springer
Abstract Prominin-1 (CD133) is a cholesterol-binding membrane glycoprotein selectively
associated with highly curved and prominent membrane structures. It is widely recognized …

Mechanisms of melanoma progression and treatment resistance: Role of cancer stem-like cells

Y Al Hmada, RT Brodell, N Kharouf, TW Flanagan… - Cancers, 2024 - mdpi.com
Simple Summary Melanoma is the third most common type of skin cancer. Melanoma is a
heterogeneous tumor, composed of genetically divergent subpopulations. These …