Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes
OD Howes, C Cummings, GE Chapman… - …, 2023 - nature.com
Over the last five decades, a large body of evidence has accrued for structural and metabolic
brain alterations in schizophrenia. Here we provide an overview of these findings, focusing …
brain alterations in schizophrenia. Here we provide an overview of these findings, focusing …
Bidirectional microglia–neuron communication in health and disease
Z Szepesi, O Manouchehrian, S Bachiller… - Frontiers in cellular …, 2018 - frontiersin.org
Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …
Mind-wandering as spontaneous thought: a dynamic framework
Most research on mind-wandering has characterized it as a mental state with contents that
are task unrelated or stimulus independent. However, the dynamics of mind-wandering …
are task unrelated or stimulus independent. However, the dynamics of mind-wandering …
Salience processing and insular cortical function and dysfunction
LQ Uddin - Nature reviews neuroscience, 2015 - nature.com
The brain is constantly bombarded by stimuli, and the relative salience of these inputs
determines which are more likely to capture attention. A brain system known as the'salience …
determines which are more likely to capture attention. A brain system known as the'salience …
Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia
The kynurenine pathway (KP) of tryptophan (TRP) catabolism links immune system
activation with neurotransmitter signaling. The KP metabolite kynurenic acid (KYNA) is …
activation with neurotransmitter signaling. The KP metabolite kynurenic acid (KYNA) is …
Brain volumes in schizophrenia: a meta-analysis in over 18 000 subjects
SV Haijma, N Van Haren, W Cahn… - Schizophrenia …, 2013 - academic.oup.com
Although structural brain alterations in schizophrenia have been demonstrated extensively,
their quantitative distribution has not been studied over the last 14 years despite advances …
their quantitative distribution has not been studied over the last 14 years despite advances …
Heterogeneity and homogeneity of regional brain structure in schizophrenia: a meta-analysis
SP Brugger, OD Howes - JAMA psychiatry, 2017 - jamanetwork.com
Importance Schizophrenia is associated with alterations in mean regional brain volumes.
However, it is not known whether the clinical heterogeneity seen in the disorder is reflected …
However, it is not known whether the clinical heterogeneity seen in the disorder is reflected …
Network-based statistic: identifying differences in brain networks
Large-scale functional or structural brain connectivity can be modeled as a network, or
graph. This paper presents a statistical approach to identify connections in such a graph that …
graph. This paper presents a statistical approach to identify connections in such a graph that …
[HTML][HTML] Disentangling the role of gray matter volume and concentration in autism spectrum disorder: A meta-analytic investigation of 25 years of voxel-based …
Despite over two decades of neuroimaging research, a unanimous definition of the pattern
of structural variation associated with autism spectrum disorder (ASD) has yet to be found …
of structural variation associated with autism spectrum disorder (ASD) has yet to be found …
Schizophrenia, neuroimaging and connectomics
Schizophrenia is frequently characterized as a disorder of brain connectivity. Neuroimaging
has played a central role in supporting this view, with nearly two decades of research …
has played a central role in supporting this view, with nearly two decades of research …