Reactive oxygen species (ROS) are produced during oxidative metabolism in aerobic
organisms. Under normal conditions, ROS production and elimination are in a relatively …

The skin is a barrier between the internal and external environment of an organism.
Depending on the species, it participates in multiple functions. The skin is the organ that …

Background Amphibian derived pro-healing peptides as molecular probes might provide a
promising strategy for development of drug candidates and elucidation of cellular and …

The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …

Since the 1980s, studies of antimicrobial peptides (AMPs) derived from anuran skin
secretions have unveiled remarkable structural diversity and a wide range of activities. This …

Despite extensive efforts to develop efficacious therapeutic approaches, the treatment of
skin wounds remains a considerable clinical challenge. Existing remedies cannot sufficiently …

Anthropogenic habitat disturbance is fundamentally altering patterns of disease
transmission and immunity across the vertebrate tree of life. Most studies linking …

Amphibian-derived wound healing peptides thus offer new intervention measures and
strategies for skin wound tissue regeneration. As novel drug lead molecules, wound healing …

Every year, millions of people develop scars due to skin injuries after trauma, surgery, or
skin burns. From the beginning of wound healing development, scar hyperplasia, and …

Amphibians are currently the most threatened vertebrate class, with the disease
chytridiomycosis being a major contributor to their global declines. Chytridiomycosis is a …