Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …

Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution
in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting …

Cryogenic electron microscopy (cryo-EM) is widely used to study biological macromolecules
that comprise regions with disorder, flexibility or partial occupancy. For example, membrane …

Many transient receptor potential (TRP) channels respond to diverse stimuli and
conditionally conduct small and large cations. Such functional plasticity is presumably …

Transient receptor potential (TRP) channels are a group of membrane proteins involved in
the transduction of a plethora of chemical and physical stimuli. These channels modulate ion …

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron
microscopy | Nature Methods Skip to main content Thank you for visiting nature.com. You are …

Cryo–electron microscopy, or simply cryo-EM, refers mainly to three very different yet closely
related techniques: electron crystallography, single-particle cryo-EM, and electron …

Cryo-electron microscopy (cryo-EM) of non-crystalline single particles is a biophysical
technique that can be used to determine the structure of biological macromolecules and …

The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

Accurate estimation of the contrast transfer function (CTF) is critical for a near-atomic
resolution cryo electron microscopy (cryoEM) reconstruction. Here, a GPU-accelerated …