Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Polymeric in situ forming depots for long-acting drug delivery systems

AK Pandya, LK Vora, C Umeyor, D Surve… - Advanced Drug Delivery …, 2023 - Elsevier
Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …

[HTML][HTML] Acne vulgaris: A review of the pathophysiology, treatment, and recent nanotechnology based advances

M Vasam, S Korutla, RA Bohara - Biochemistry and Biophysics Reports, 2023 - Elsevier
Abstract Background Globally, Acne Vulgaris is a widespread, chronic inflammatory
condition of the pilosebaceous follicles. Acne is not fatal, but depending on its severity, it can …

Nanotechnology for topical drug delivery to the anterior segment of the eye

A Vaneev, V Tikhomirova, N Chesnokova… - International journal of …, 2021 - mdpi.com
Topical drug delivery is one of the most challenging aspects of eye therapy. Eye drops are
the most prevalent drug form, especially for widely distributed anterior segment eye …

Perspectives on cutting‐edge nanoparticulate drug delivery technologies based on lipids and their applications

B Maddiboyina, Ramaiah… - Chemical Biology & …, 2023 - Wiley Online Library
Numerous nanotech arenas in therapeutic biology have recently provided a scientific
platform to manufacture a considerable swath of unique chemical entities focusing on drugs …

Formulation, optimization and characterization of raloxifene hydrochloride loaded PLGA nanoparticles by using Taguchi design for breast cancer application

B Maddiboyina, H Roy, RK Nakkala… - Chemical Biology & …, 2023 - Wiley Online Library
Multidrug resistance in breast cancer and the associated side‐effects of anticancer therapies
are significant hurdles in chemotherapy‐based treatment. Biodegradable polymeric nano …

An insight of nanogels as novel drug delivery system with potential hybrid nanogel applications

B Maddiboyina, PK Desu, M Vasam… - Journal of …, 2022 - Taylor & Francis
Nanogels are cross-linked, nano-sized hydrogels with dimensions ranging from 20 to 200
nm. Nanogel-based nanoplatforms have proven to be an excellent choice for …

Design, development, and evaluation of spray dried flurbiprofen loaded sustained release polymeric nanoparticles using QBD approach to manage inflammation

S Mandpe, E Kole, V Parate, A Chatterjee… - Drying …, 2023 - Taylor & Francis
Spray-dried Flurbiprofen (FLB) loaded polymeric nanoformulation using Eudragit L 100 and
Ethylcellulose. They were optimized and evaluated. This study determined drug release (%) …

Targeted drug delivery vehicles mediated by nanocarriers and aptamers for posterior eye disease therapeutics: Barriers, recent advances and potential opportunities

T Zhang, X **, N Zhang, X Jiao, Y Ma, R Liu… - …, 2022 - iopscience.iop.org
Nanomedicine and aptamer have excellent potential in giving play to passive and active
targeting respectively, which are considered to be effective strategies in the retro-ocular drug …

Development, QbD-based optimisation, in-vivo pharmacokinetics, and ex-vivo evaluation of Eudragit® RS 100 loaded flurbiprofen nanoparticles for oral drug …

S Mandpe, E Kole, V Parate, A Chatterjee… - Journal of …, 2024 - Taylor & Francis
This study aims to develop and evaluate flurbiprofen-loaded polymeric nanoparticles to
achieve sustained drug release, enhancing therapeutic efficacy and minimising dosing …