Computational fluid dynamics as a risk assessment tool for aneurysm rupture

Y Murayama, S Fujimura, T Suzuki, H Takao - Neurosurgical focus, 2019 - thejns.org
OBJECTIVE The authors reviewed the clinical role of computational fluid dynamics (CFD) in
assessing the risk of intracranial aneurysm rupture. METHODS A literature review was …

Disturbed flow's impact on cellular changes indicative of vascular aneurysm initiation, expansion, and rupture: A pathological and methodological review

K Sunderland, J Jiang, F Zhao - Journal of cellular physiology, 2022 - Wiley Online Library
Aneurysms are malformations within the arterial vasculature brought on by the structural
breakdown of the microarchitecture of the vessel wall, with aneurysms posing serious health …

Real-world variability in the prediction of intracranial aneurysm wall shear stress: the 2015 international aneurysm CFD challenge

K Valen-Sendstad, AW Bergersen… - Cardiovascular …, 2018 - Springer
Purpose Image-based computational fluid dynamics (CFD) is widely used to predict
intracranial aneurysm wall shear stress (WSS), particularly with the goal of improving rupture …

Development and internal validation of an aneurysm rupture probability model based on patient characteristics and aneurysm location, morphology, and …

FJ Detmer, BJ Chung, F Mut, M Slawski… - International journal of …, 2018 - Springer
Purpose Unruptured cerebral aneurysms pose a dilemma for physicians who need to weigh
the risk of a devastating subarachnoid hemorrhage against the risk of surgery or …

The relationship of morphological-hemodynamic characteristics, inflammation, and remodeling of aneurysm wall in unruptured intracranial aneurysms

Q Liu, Y Zhang, J Yang, Y Yang, M Li, S Chen… - Translational stroke …, 2022 - Springer
Aneurysm wall remodeling (AWR) is an important pathological characteristic in aneurysm
wall, which was characterized by abnormal histological structure and inflammation …

Multimodal validation of focal enhancement in intracranial aneurysms as a surrogate marker for aneurysm instability

N Larsen, C Flüh, S Saalfeld, S Voß, G Hille, D Trick… - Neuroradiology, 2020 - Springer
Purpose Circumferential enhancement on MR vessel wall imaging has been proposed as a
biomarker of a higher risk of rupture in intracranial aneurysms. Focal enhancement is …

Comparison of statistical learning approaches for cerebral aneurysm rupture assessment

FJ Detmer, D Lückehe, F Mut, M Slawski… - International journal of …, 2020 - Springer
Purpose Incidental aneurysms pose a challenge to physicians who need to decide whether
or not to treat them. A statistical model could potentially support such treatment decisions …

Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—phase II: rupture risk assessment

P Berg, S Voß, G Janiga, S Saalfeld… - International journal of …, 2019 - Springer
Purpose Assessing the rupture probability of intracranial aneurysms (IAs) remains
challenging. Therefore, hemodynamic simulations are increasingly applied toward …

Hemodynamics of cerebral aneurysms: Connecting medical imaging and biomechanical analysis

VL Rayz, AA Cohen-Gadol - Annual review of biomedical …, 2020 - annualreviews.org
In the last two decades, numerous studies have conducted patient-specific computations of
blood flow dynamics in cerebral aneurysms and reported correlations between various …

Review of the development of hemodynamic modeling techniques to capture flow behavior in arteries affected by aneurysm, atherosclerosis, and stenting

PN Williamson, PD Docherty… - Journal of …, 2022 - asmedigitalcollection.asme.org
Cardiovascular diseases (CVDs) are the leading cause of death in the developed world.
CVD can include atherosclerosis, aneurysm, dissection, or occlusion of the main arteries …