[HTML][HTML] NAC, NAC, Knockin'on Heaven's door: Interpreting the mechanism of action of N-acetylcysteine in tumor and immune cells
B Kalyanaraman - Redox Biology, 2022 - Elsevier
N-acetylcysteine (NAC) has been used as a direct scavenger of reactive oxygen species
(hydrogen peroxide, in particular) and an antioxidant in cancer biology and immuno …
(hydrogen peroxide, in particular) and an antioxidant in cancer biology and immuno …
Direct Interaction between N-Acetylcysteine and Cytotoxic Electrophile—An Overlooked In Vitro Mechanism of Protection
P Mlejnek - Antioxidants, 2022 - mdpi.com
In laboratory experiments, many electrophilic cytotoxic agents induce cell death
accompanied by reactive oxygen species (ROS) production and/or by glutathione (GSH) …
accompanied by reactive oxygen species (ROS) production and/or by glutathione (GSH) …
Visualization of biothiols and HClO in cancer therapy via a multi-responsive fluorescent probe
X Yang, J Liu, P **e, X Han, D Zhang, Y Ye… - Sensors and Actuators B …, 2021 - Elsevier
Cancer is among the most important diseases threatening human life and health, and drug
chemotherapy is an effective method which can be used to treat cancer. Last several years …
chemotherapy is an effective method which can be used to treat cancer. Last several years …
[HTML][HTML] Understanding immune-modulatory efficacy in vitro
Boosting or suppressing our immune system represents an attractive adjunct in the
treatment of infections including SARS-CoV-2, cancer, AIDS, malnutrition, age related …
treatment of infections including SARS-CoV-2, cancer, AIDS, malnutrition, age related …
Formulation of a dual drug-loaded nanoparticulate co-delivery hydrogel system and its validation in rheumatoid arthritis animal model
Rheumatoid arthritis (RA), a systemic autoimmune disease that dramatically affects patients'
quality of life. Given the intricacy of RA's pathophysiology, no single treatment can …
quality of life. Given the intricacy of RA's pathophysiology, no single treatment can …
A dual-response NIR probe reveals positive correlation between biothiols and viscosity under cellular stress change
S Li, F Huo, Y Wen, C Yin - Chemical Communications, 2022 - pubs.rsc.org
A mitochondrial targeted NIR fluorescent probe NIR-NBD was designed and developed for
the detection of biothiols and viscosity. Furthermore, a positive correlation between the …
the detection of biothiols and viscosity. Furthermore, a positive correlation between the …
Quantitative chemical proteomics reveals that phenethyl isothiocyanate covalently targets BID to promote apoptosis
X Dong, X Yu, M Lu, Y Xu, L Zhou, T Peng - Cell Death Discovery, 2024 - nature.com
Naturally occurring isothiocyanates (ITCs) found in cruciferous vegetables, such as benzyl
isothiocyanate (BITC), phenethyl isothiocyanate (PEITC), and sulforaphane (SFN), have …
isothiocyanate (BITC), phenethyl isothiocyanate (PEITC), and sulforaphane (SFN), have …
Reviewing the prospective pharmacological potential of isothiocyanates in fight against female-specific cancers
Simple Summary Gynecological cancers are among the most commonly diagnosed cancers
in women globally. Despite advancements in diagnostics and treatments, these cancers …
in women globally. Despite advancements in diagnostics and treatments, these cancers …
Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a leading liver cancer that significantly impacts global
life expectancy and remains challenging to treat due to often late diagnoses. Despite …
life expectancy and remains challenging to treat due to often late diagnoses. Despite …
The therapeutic effect of wasp venom (Vespa magnifica, Smith) and its effective part on rheumatoid arthritis fibroblast-like synoviocytes through modulating …
LL Ni, YH Che, HM Sun, B Wang, MY Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a chronic inflammatory
disease that is related to the aberrant proliferation of fibroblast-like synoviocytes (FLS) …
disease that is related to the aberrant proliferation of fibroblast-like synoviocytes (FLS) …