Genome editing offers promising solutions to genetic disorders by editing DNA sequences
or modulating gene expression. The clustered regularly interspaced short palindromic …

The traditional healthcare system is at the doorstep for entering into the arena of molecular
medicine. The enormous knowledge and ongoing research have now been able to …

Gene therapy has historically been defined as the addition of new genes to human cells.
However, the recent advent of genome-editing technologies has enabled a new paradigm in …

Recent advances in the development of genome editing technologies based on
programmable nucleases have substantially improved our ability to make precise changes …

Targeted genome editing using engineered nucleases has rapidly gone from being a niche
technology to a mainstream method used by many biological researchers. This widespread …

Targeted mutagenesis, editing of endogenous maize (Zea mays) genes, and site-specific
insertion of a trait gene using clustered regularly interspaced short palindromic repeats …

Genome editing by sequence-specific nucleases (SSNs) has revolutionized biology by
enabling targeted modifications of genomes. Although routine plant genome editing …

Recently discovered bacteria and archaea adaptive immune system consisting of clustered
regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) …

The move from reading to writing the human genome offers new opportunities to improve
human health. The United States National Institutes of Health (NIH) Somatic Cell Genome …

Sequence-specific nucleases enable facile editing of higher eukaryotic genomic DNA;
however, targeted modification of plant genomes remains challenging due to ineffective …