Role of protein glycosylation in host-pathogen interaction

B Lin, X Qing, J Liao, K Zhuo - Cells, 2020 - mdpi.com
Host-pathogen interactions are fundamental to our understanding of infectious diseases.
Protein glycosylation is one kind of common post-translational modification, forming …

[HTML][HTML] Taxonomic distribution and molecular evolution of mytilectins

M Gerdol, DE Nerelli, N Martelossi, Y Ogawa, Y Fujii… - Marine Drugs, 2023 - mdpi.com
R-type lectins are a widespread group of sugar-binding proteins found in nearly all domains
of life, characterized by the presence of a carbohydrate-binding domain that adopts a β …

Immunity in molluscs: recognition and effector mechanisms, with a focus on bivalvia

M Gerdol, M Gomez-Chiarri, MG Castillo… - Advances in …, 2018 - Springer
The study of molluscan immune systems, in particular those of bivalve molluscs (eg, clams,
oysters, scallops, mussels), has experienced great growth in recent decades, mainly due to …

A genomic and transcriptomic analysis of the C-Type lectin Gene Family reveals highly expanded and Diversified repertoires in Bivalves

A Saco, H Suárez, B Novoa, A Figueras - Marine Drugs, 2023 - mdpi.com
C-type lectins belong to a widely conserved family of lectins characterized in Metazoa. They
show important functional diversity and immune implications, mainly as pathogen …

The immune system of the freshwater zebra mussel, Dreissena polymorpha, decrypted by proteogenomics of hemocytes and plasma compartments

M Lepretre, C Almunia, J Armengaud, A Salvador… - Journal of …, 2019 - Elsevier
The immune system of bivalves is of great interest since it reflects the health status of these
organisms during stressful conditions. While immune molecular responses are well …

Crystal structure of MytiLec, a galactose-binding lectin from the mussel Mytilus galloprovincialis with cytotoxicity against certain cancer cell types

D Terada, F Kawai, H Noguchi, S Unzai, I Hasan… - Scientific Reports, 2016 - nature.com
MytiLec is a lectin, isolated from bivalves, with cytotoxic activity against cancer cell lines that
express globotriaosyl ceramide, Galα (1, 4) Galβ (1, 4) Glcα1-Cer, on the cell surface …

Molecular and functional characterization of a glycosylated galactose-binding lectin from Mytilus californianus

E García-Maldonado, P Cano-Sánchez… - Fish & Shellfish …, 2017 - Elsevier
Lectins play crucial roles for innate immune responses in invertebrates by recognizing and
eliminating pathogens. In this study, a lectin from the mussel Mytilus californianus (MCL) …

First insights into the repertoire of secretory lectins in rotifers

M Gerdol - Marine Drugs, 2022 - mdpi.com
Due to their high biodiversity and adaptation to a mutable and challenging environment,
aquatic lophotrochozoan animals are regarded as a virtually unlimited source of bioactive …

Immune-related genes in gastropods and bivalves: a comparative overview

M Gerdol - Invertebrate Survival Journal, 2017 - arts.units.it
The biological diversity of molluscs and their adaptation to highly diverse environments offer
a unique opportunity for studying the evolution of the innate immune system in invertebrates …

Genetic and molecular basis of the immune system in the brachiopod Lingula anatina

M Gerdol, YJ Luo, N Satoh, A Pallavicini - Developmental & Comparative …, 2018 - Elsevier
The extension of comparative immunology to non-model systems, such as mollusks and
annelids, has revealed an unexpected diversity in the complement of immune receptors and …