Podocytes are highly specialized cells of the kidney glomerulus that wrap around capillaries
and that neighbor cells of the Bowman's capsule. When it comes to glomerular filtration …

Organ fibrogenesis is characterized by a common pathophysiological final pathway
independent of the underlying progressive disease of the respective organ. This makes it …

Although tissue-resident-memory T (T RM) cells, a recently identified non-circulating
memory T cell population, play a crucial role in mediating local immune responses and …

Spatial multi-omic studies have emerged as a promising approach to comprehensively
analyze cells in tissues, enabling the joint analysis of multiple data modalities like …

The mechanisms driving the development of extracapillary lesions in focal segmental
glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) remain poorly …

Over the past 2 decades, scoring systems for multiple glomerular diseases have emerged,
as have consortia of pathologists and nephrologists for the study of glomerular diseases …

Podocyte injury is central to many forms of kidney disease, but transcriptional signatures
reflecting podocyte injury and compensation mechanisms are challenging to analyze in vivo …

Podocytes and parietal epithelial cells (PECs) are among the few principal cell types within
the kidney glomerulus, the former serving as a crucial constituent of the kidney filtration …

A key feature of glomerular diseases such as crescentic glomerulonephritis and focal
segmental glomerulosclerosis is the activation, migration and proliferation of parietal …

Beside the classical flat parietal epithelial cells (PECs), we investigated proximal tubular
epithelial-like cells, a neglected subgroup of PECs. These cells, termed cuboidal PECs …