Pneumonia, such as acute lung injury (ALI), has been a type of lethal disease that is
generally caused by uncontrolled inflammatory response and excessive generation of …

Preclinical and clinical studies suggest that inflammation and vascular dysfunction
contribute to the pathogenesis of major depressive disorder (MDD). Chronic social stress …

Lung epithelium is constantly exposed to the environment and is critically important for the
orchestration of initial responses to infectious organisms, toxins, and allergic stimuli, and …

Abstract Claudin-5 (CLDN5) is an essential component of tight junctions (TJs) and is critical
for the integrity of the blood-brain barrier (BBB), ensuring homeostasis and protection from …

Objective Alveolar epithelial barrier dysfunction in response to inflammatory reaction
contributes to pulmonary edema in acute lung injury (ALI). Irisin, a newly-found myokine …

Acute lung injury (ALI) is a syndrome caused by an excessive inflammatory response
characterized by intractable hypoxemia both inside and outside the lung, for which effective …

Background and Purpose Respiratory diseases have become a global health problem and
may lead to acute lung injury (ALI) in severe cases. ALI progression is associated with …

Rationale: Development of novel nanomedicines to inhibit pro-inflammatory cytokine
expression and reactive oxygen species (ROS) generation for anti-inflammatory therapy of …

Background Lung injury is a vital contributor of mortality in septic patients. Our previous
studies have found that molecular hydrogen (H 2), which has anti-oxidant, anti-inflammatory …

Rationale Alveolar epithelial cell death, inflammation, and oxidative stress are typical
features of acute lung injury (ALI). Aloperine (Alo), an alkaloid isolated from Sophora …