Chronic inflammation plays an imperative role in the onset and progression of chronic
diseases including diabetes, hypertension, cancer, allergies, and asthma. Diet can modulate …

Inflammation plays a key role in diseases such as diabetes, asthma, cardiovascular
diseases and cancer. Diet can influence different stages of inflammation and can have an …

CK2 (casein kinase 2) is a serine/threonine protein kinase that is ubiquitous in eukaryotic
cells and plays important roles in a variety of cellular functions, including cell growth …

Flavonoids are polyphenolic phytochemicals produced in fruits, nuts and vegetables and
dietary consumption of these structurally diverse compounds is associated with multiple …

In this comprehensive review we tried to reassess the role of phytochemicals in cancer
chemoprevention. The exploration of the “synergistic effect” concept, advocating combined …

Chronic kidney disease (CKD) is a progressive systemic disease, which changes the
function and structure of the kidneys irreversibly over months or years. The final common …

Building on the pyrazolopyrimidine CK2 (casein kinase 2) inhibitor scaffold, we designed a
small targeted library. Through comprehensive evaluation of inhibitor selectivity, we …

Flavonoids are important bioactive phenolic compounds abundant in plants and exhibit
different therapeutic potentials. A wound is a significant problem in diabetic individuals. A …

Food-derived flavonoid quercetin, widely distributed in onions, apples, and tea, is able to
inhibit growth of various cancer cells indicating that this compound can be considered as a …

Increased consumption of fruits and vegetables can represent an easy strategy to
significantly reduce the incidence of cancer. From this observation, derived mostly from …