Synthesis and reactivity of propargylamines in organic chemistry

K Lauder, A Toscani, N Scalacci… - Chemical reviews, 2017 - ACS Publications
Propargylamines are a versatile class of compounds which find broad application in many
fields of chemistry. This review aims to describe the different strategies developed so far for …

A new avenue to the synthesis of highly substituted pyrroles: synthesis from N-propargylamines

E Vessally - RSC advances, 2016 - pubs.rsc.org
Pyrroles have attracted much attention due to their potential biological activities. Develo**
more efficient methods for the generation of pyrrole cores with unusual substitution patterns …

Unveiling the biocatalytic aromatizing activity of monoamine oxidases MAO-N and 6-HDNO: development of chemoenzymatic cascades for the synthesis of pyrroles

N Scalacci, GW Black, G Mattedi, NL Brown… - ACS …, 2017 - ACS Publications
A chemoenzymatic cascade process for the sustainable production of pyrroles has been
developed. Pyrroles were synthesized by exploiting the previously unexplored aromatizing …

[PDF][PDF] Synthesis of pyrrole and substituted pyrroles

D Tzankova, S Vladimirova, L Peikova… - Journal of Chemical …, 2018 - researchgate.net
Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of
activities. The combination of different pharmacophores in a pyrrole ring system has led to …

Transition Metal‐Catalyzed and Metal‐Free Cyclization Reactions of Alkynes with Nitrogen‐Containing Substrates: Synthesis of Pyrrole Derivatives

JSS Neto, G Zeni - ChemCatChem, 2020 - Wiley Online Library
This review describes the efforts in the synthesis of pyrrole derivatives using the reaction of
alkynes with nitrogen‐compounds under transition metal‐catalyzed and metal‐free …

Design of efficient benzimidazole-derived N-heterocyclic carbene Ag (I) catalysts for aldehyde–amine–alkyne coupling

Z Nawaz, N Gürbüz, MN Zafar, MN Tahir… - Journal of Molecular …, 2024 - Elsevier
A mild catalytic protocol for aldehyde, amine, and alkyne coupling (A 3-coupling) allows for
the selective synthesis of propargyl amines using 5, 6-dimethylbenzimidazole-derived N …

K2S2O8-Mediated Synthesis of Highly Functionalized Pyrroles via Oxidative Self-Dimerization of N-Propargylamines

BK Behera, AK Sahu, NR Devi… - The Journal of Organic …, 2021 - ACS Publications
An efficient methodology has been developed for the synthesis of tetra-and pentasubstituted
pyrroles via oxidative self-dimerization of N-propargylamines catalyzed by silver benzoate in …

Controlled alternating metathesis copolymerization of terminal alkynes

S Pal, I Mandal, AFM Kilbinger - ACS Macro Letters, 2022 - ACS Publications
Terminal alkynes display high reactivity toward Ru-carbene metathesis catalysts. However,
the formation of a less reactive bulky carbene hinders their homopolymerization …

Copper(I)-Catalyzed Dearomative (3 + 2) Cycloaddition of 3-Nitroindoles with Propargylic Nucleophiles: An Access to Cyclopenta[b]indolines

J Ling, D Mara, B Roure, M Laugeois… - The Journal of Organic …, 2020 - ACS Publications
The copper (I)-catalyzed dearomatization of 3-nitroindoles with propargylic nucleophiles is
described. In mild reaction conditions, this original dearomative (3+ 2) cycloaddition process …

Application of Olefin Metathesis in the Synthesis of Carbo-and Heteroaromatic Compounds—Recent Advances

S Rogalski, C Pietraszuk - Molecules, 2023 - mdpi.com
The olefin metathesis reaction has found numerous applications in organic synthesis. This is
due to a number of advantages, such as the tolerance of most functional groups and …