Protoglobin‐Catalyzed Formation of cis‐Trifluoromethyl‐Substituted Cyclopropanes by Carbene Transfer

L Schaus, A Das, AM Knight… - Angewandte …, 2023‏ - Wiley Online Library
Abstract Trifluoromethyl‐substituted cyclopropanes (CF3‐CPAs) constitute an important
class of compounds for drug discovery. While several methods have been developed for …

Protoglobin: structure and ligand-binding properties

A Pesce, M Bolognesi, M Nardini - Advances in Microbial Physiology, 2013‏ - Elsevier
Protoglobin is the first globin identified in Archaea; its biological role is still unknown,
although it can bind O 2, CO and NO reversibly in vitro. The X-ray structure of …

A novel single sensor hemoglobin domain from the thermophilic cyanobacteria Thermosynechococcus elongatus BP-1 exhibits higher pH but lower thermal stability …

S Mathur, SK Yadav, K Yadav, S Bhatt… - International Journal of …, 2023‏ - Elsevier
Thermosynechococcus elongatus-BP1 belongs to the class of photoautotrophic
cyanobacterial organisms. The presence of chlorophyll a, carotenoids, and phycocyanobilin …

Roles of N-and C-terminal domains in the ligand-binding properties of cytoglobin

S Hanai, H Tsu**o, T Yamashita, R Torii… - Journal of Inorganic …, 2018‏ - Elsevier
Cytoglobin (Cygb) is a member of the hexacoordinated globin protein family and is
expressed ubiquitously in rat and human tissues. Although Cygb is reportedly upregulated …

Interaction of nitrite with ferric protoglobin from Methanosarcina acetivorans–an interesting model for spectroscopic studies of the haem–ligand interaction

R Sgammato, N Van Brempt, R Aerts… - Dalton …, 2023‏ - pubs.rsc.org
Protoglobin from Methanosarcina acetivorans (MaPgb) is a dimeric globin belonging to the
same lineage of the globin superfamily as globin-coupled sensors. A putative role in the …

Structure and Haem-Distal Site Plasticity in Methanosarcina acetivorans Protoglobin

A Pesce, L Tilleman, J Donne, E Aste, P Ascenzi… - PLoS …, 2013‏ - journals.plos.org
Protoglobin from Methanosarcina acetivorans C2A (Ma Pgb), a strictly anaerobic
methanogenic Archaea, is a dimeric haem-protein whose biological role is still unknown. As …

Nitrite-Reductase and Peroxynitrite Isomerization Activities of Methanosarcina acetivorans Protoglobin

P Ascenzi, L Leboffe, A Pesce, C Ciaccio, D Sbardella… - PLoS …, 2014‏ - journals.plos.org
Within the globin superfamily, protoglobins (Pgb) belong phylogenetically to the same
cluster of two-domain globin-coupled sensors and single-domain sensor globins. Multiple …

Structural and Functional Significance of the N- and C-Terminal Appendages in Arabidopsis Truncated Hemoglobin

N Mukhi, S Dhindwal, S Uppal, A Kapoor, R Arya… - Biochemistry, 2016‏ - ACS Publications
Plant hemoglobins constitute three distinct groups: symbiotic, nonsymbiotic, and truncated
hemoglobins. Structural investigation of symbiotic and nonsymbiotic (class I) hemoglobins …

Studies on Scaling Throughput in Protein Engineering

LJN Schaus - 2025‏ - search.proquest.com
Studies on Scaling Throughput in Protein Engineering Page 1 Studies on Scaling Throughput in
Protein Engineering Thesis by Lucas Jean Nicolas Schaus In Partial Fulfillment of the …

Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans

L Tilleman, S Abbruzzetti, C Ciaccio, G De Sanctis… - Plos one, 2015‏ - journals.plos.org
Studies of CO ligand binding revealed that two protein states with different ligand affinities
exist in the protoglobin from Methanosarcina acetivorans (in Ma Pgb*, residue Cys (E20) …