[HTML][HTML] Nanoparticle tracking analysis: an effective tool to characterize extracellular vesicles

G Kowkabany, Y Bao - Molecules, 2024 - mdpi.com
Extracellular vesicles (EVs) are membrane-enclosed particles that have attracted much
attention for their potential in disease diagnosis and therapy. However, the clinical …

Cytokines and soluble mediators as architects of tumor microenvironment reprogramming in cancer therapy

S Xu, Q Wang, W Ma - Cytokine & Growth Factor Reviews, 2024 - Elsevier
Navigating the intricate landscape of the tumor microenvironment (TME) unveils a pivotal
arena for cancer therapeutics, where cytokines and soluble mediators emerge as double …

[HTML][HTML] Exosomes: key factors in ovarian cancer peritoneal metastasis and drug resistance

M Shao, Y Gao, X Xu, DW Chan, J Du - Biomolecules, 2024 - mdpi.com
Ovarian cancer remains a leading cause of death among gynecological cancers, largely due
to its propensity for peritoneal metastasis and the development of drug resistance. This …

NIR-II Light-Driven Genetically Engineered Exosome Nanocatalysts for Efficient Phototherapy against Glioblastoma

X Fang, R Gong, D Yang, C Li, Y Zhang… - Journal of the …, 2024 - ACS Publications
Glioblastoma (GBM) poses a significant therapeutic challenge due to its invasive nature and
limited drug penetration through the blood–brain barrier (BBB). In response, here we …

[HTML][HTML] Extracellular Vesicles: Advanced Tools for Disease Diagnosis, Monitoring, and Therapies

P Lorite, JN Domínguez, T Palomeque… - International Journal of …, 2024 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous group of membrane-encapsulated vesicles
released by cells into the extracellular space. They play a crucial role in intercellular …

[HTML][HTML] Melanoma-derived extracellular vesicles transfer proangiogenic factors

M Wilczak, M Surman, M PRZYBYłO - Oncology research, 2025 - pmc.ncbi.nlm.nih.gov
Angiogenesis, the expansion of pre-existing vascular networks, is crucial for normal organ
growth and tissue repair, but is also involved in various pathologies, including inflammation …

Harnessing the tumor microenvironment: targeted cancer therapies through modulation of epithelial-mesenchymal transition

A Glaviano, HSH Lau, LM Carter, EHC Lee… - Journal of Hematology & …, 2025 - Springer
The tumor microenvironment (TME) is integral to cancer progression, impacting metastasis
and treatment response. It consists of diverse cell types, extracellular matrix components …

Role of Extracellular Vesicles in the Progression of Brain Tumors

G Schiera, CM Di Liegro, F Vento, I Di Liegro - Biology, 2024 - pmc.ncbi.nlm.nih.gov
Simple Summary Brain tumors are among the most aggressive and difficult to cope with
cancers among the many kinds which can affect the human body. These properties are due …

[HTML][HTML] Prospects and Current Challenges of Extracellular Vesicle-Based Biomarkers in Cancer

SR Lawrence, KM Shah - Biology, 2024 - mdpi.com
Simple Summary Cancer presents a significant global health challenge, particularly in
ageing populations, emphasising the importance of early detection to facilitate personalised …

Exosomal lncRNA XIST promotes perineural invasion of pancreatic cancer cells via miR-211-5p/GDNF

K Cheng, J Pan, Q Liu, Y Ji, L Liu, X Guo, Q Wang, S Li… - Oncogene, 2024 - nature.com
Perineural invasion (PNI) is an essential form of tumor metastasis in multiple malignant
cancers, such as pancreatic cancer, prostate cancer, and head and neck cancer. Growing …