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Dynamic whole-body PET imaging: principles, potentials and applications
Purpose In this article, we discuss dynamic whole-body (DWB) positron emission
tomography (PET) as an imaging tool with significant clinical potential, in relation to …
tomography (PET) as an imaging tool with significant clinical potential, in relation to …
Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …
with water between the wraps. The measurement of damage to the myelin sheaths, the …
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
Fluorodeoxyglucose positron emission tomography (PET) studies have found that patients
with Alzheimer's dementia (AD) have abnormally low rates of cerebral glucose metabolism …
with Alzheimer's dementia (AD) have abnormally low rates of cerebral glucose metabolism …
Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis
PET studies have been performed using the amyloid binding radiotracer Pittsburgh
Compound B (PIB). Previous quantitative analyses using arterial blood showed that the …
Compound B (PIB). Previous quantitative analyses using arterial blood showed that the …
Longitudinal PET evaluation of cerebral metabolic decline in dementia: a potential outcome measure in Alzheimer's disease treatment studies
OBJECTIVE: It is well established that regional cerebral metabolic rates for glucose
assessed by [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET) in …
assessed by [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET) in …
Correlations between apolipoprotein E ε4 gene dose and brain-imaging measurements of regional hypometabolism
Patients with Alzheimer's disease (AD) have abnormally low positron emission tomography
(PET) measurements of the cerebral metabolic rate for glucose (CMRgl) in regions of the …
(PET) measurements of the cerebral metabolic rate for glucose (CMRgl) in regions of the …
Image-derived input function for brain PET studies: many challenges and few opportunities
Quantitative positron emission tomography (PET) brain studies often require that the input
function be measured, typically via arterial cannulation. Image-derived input function (IDIF) …
function be measured, typically via arterial cannulation. Image-derived input function (IDIF) …
An update on the use of image-derived input functions for human PET studies: new hopes or old illusions?
Background The need for arterial blood data in quantitative PET research limits the wider
usability of this imaging method in clinical research settings. Image-derived input function …
usability of this imaging method in clinical research settings. Image-derived input function …
Whole-body parametric imaging of 18F-FDG PET using uEXPLORER with reduced scanning time
Parametric imaging of the net influx rate (Ki) in 18F-FDG PET has been shown to provide
improved quantification and specificity for cancer detection compared with SUV imaging …
improved quantification and specificity for cancer detection compared with SUV imaging …
Tracer kinetic modeling in PET
The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with
modern instrumentation are key components to successful developments in PET. Clever …
modern instrumentation are key components to successful developments in PET. Clever …