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Structural biology of SARS-CoV-2 and implications for therapeutic development
H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), is an unprecedented global health crisis. However, therapeutic options for …
(SARS-CoV-2), is an unprecedented global health crisis. However, therapeutic options for …
[HTML][HTML] Autophagy in inflammation, infection, and immunometabolism
V Deretic - Immunity, 2021 - cell.com
Autophagy is a quality-control, metabolic, and innate immunity process. Normative
autophagy affects many cell types, including hematopoietic as well as non-hematopoietic …
autophagy affects many cell types, including hematopoietic as well as non-hematopoietic …
The reactome pathway knowledgebase 2022
Abstract The Reactome Knowledgebase (https://reactome. org), an Elixir core resource,
provides manually curated molecular details across a broad range of physiological and …
provides manually curated molecular details across a broad range of physiological and …
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
To combat future severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health …
and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health …
Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb
M Khan, SJ Yoo, M Clijsters, W Backaert, A Vanstapel… - Cell, 2021 - cell.com
Anosmia, the loss of smell, is a common and often the sole symptom of COVID-19. The onset
of the sequence of pathobiological events leading to olfactory dysfunction remains obscure …
of the sequence of pathobiological events leading to olfactory dysfunction remains obscure …
[HTML][HTML] Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy
The December 2019 outbreak of a novel respiratory virus, SARS-CoV-2, has become an
ongoing global pandemic due in part to the challenge of identifying symptomatic …
ongoing global pandemic due in part to the challenge of identifying symptomatic …
[HTML][HTML] β-Coronaviruses use lysosomes for egress instead of the biosynthetic secretory pathway
S Ghosh, TA Dellibovi-Ragheb, A Kerviel, E Pak, Q Qiu… - Cell, 2020 - cell.com
Summary β-Coronaviruses are a family of positive-strand enveloped RNA viruses that
includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is …
includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is …
[HTML][HTML] Type I and type III interferons–induction, signaling, evasion, and application to combat COVID-19
A Park, A Iwasaki - Cell host & microbe, 2020 - cell.com
Coronavirus disease 2019 (COVID-19) is a global pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Without approved antiviral therapeutics …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Without approved antiviral therapeutics …
Immune response, inflammation, and the clinical spectrum of COVID-19
LF García - Frontiers in immunology, 2020 - frontiersin.org
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly
extended to become a global sanitary and economic emergency. Its etiological agent is the …
extended to become a global sanitary and economic emergency. Its etiological agent is the …
Type I and III interferon responses in SARS-CoV-2 infection
Abstract Coronavirus disease 2019 (COVID-19), the current pandemic disease, is caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Type I and III …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Type I and III …