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Venous thromboembolism: review of Clinical challenges, Biology, Assessment, Treatment, and modeling
Venous thromboembolism (VTE) is a massive clinical challenge, annually affecting millions
of patients globally. VTE is a particularly consequential pathology, as incidence is correlated …
of patients globally. VTE is a particularly consequential pathology, as incidence is correlated …
[HTML][HTML] Simulating the hydrodynamic conditions of the human ascending colon: a digital twin of the dynamic colon model
M Schütt, C O'farrell, K Stamatopoulos, CL Hoad… - Pharmaceutics, 2022 - mdpi.com
The performance of solid oral dosage forms targeting the colon is typically evaluated using
standardised pharmacopeial dissolution apparatuses. However, these fail to replicate …
standardised pharmacopeial dissolution apparatuses. However, these fail to replicate …
Fluid-structure interaction of blood flow around a vein valve
Introduction: Venous valves are a type of one-way valves which conduct blood flow toward
the heart and prevent its backflow. Any malfunction of these organs may cause serious …
the heart and prevent its backflow. Any malfunction of these organs may cause serious …
An improved particle method for simulating Fluid-Structure Interactions: The multi-resolution SPH-VCPM approach
In this paper, the computational efficiency of our previous Smoothed Particle Hydrodynamics-
Volume Compensated Particle Method (SPH-VCPM) is enhanced by incorporating a multi …
Volume Compensated Particle Method (SPH-VCPM) is enhanced by incorporating a multi …
A coupled smoothed particle hydrodynamics-volume compensated particle method (SPH-VCPM) for fluid structure interaction (FSI) modelling
A new unified particle model that couples the Smoothed Particle Hydrodynamics (SPH) and
a discontinuous approach known as the Volume Compensated Particle Method (VCPM) is …
a discontinuous approach known as the Volume Compensated Particle Method (VCPM) is …
[HTML][HTML] A novel mono-physics particle-based approach for the simulation of cardiovascular fluid-structure interaction problems
Background and objective Fluid-structure interaction (FSI) is required in the study of several
cardiovascular engineering problems were the mutual interaction between the pulsatile …
cardiovascular engineering problems were the mutual interaction between the pulsatile …
Modelling of thrombus formation using smoothed particle hydrodynamics method
In this paper a novel model, based on the smoothed particle hydrodynamics (SPH) method,
is proposed to simulate thrombus formation. This describes the main phases of the …
is proposed to simulate thrombus formation. This describes the main phases of the …
Numerical simulation of dissolution of solid particles in fluid flow using the SPH method
Purpose The purpose of this paper is to numerically study the dissolution of solid particles
using the smoothed particle hydrodynamics (SPH) method. Design/methodology/approach …
using the smoothed particle hydrodynamics (SPH) method. Design/methodology/approach …
Deformation and rupture of compound cells under shear: A discrete multiphysics study
This paper develops a three-dimensional numerical model for the simulation of cells in
simple shear flow. The model is based on Discrete Multi-Physics (DMP), a meshless particle …
simple shear flow. The model is based on Discrete Multi-Physics (DMP), a meshless particle …
[HTML][HTML] Development of a digital twin of a tablet that mimics a real solid dosage form: Differences in the dissolution profile in conventional mini-USP II and a …
The performance of colon-targeted solid dosage forms is commonly assessed using
standardised pharmacopeial dissolution apparatuses like the USP II or the miniaturised …
standardised pharmacopeial dissolution apparatuses like the USP II or the miniaturised …