Bacteria use their genetic material with great effectiveness to make the right products in the
correct amounts at the appropriate time. Studying bacterial transcription initiation in …

The expression of genes is regularly characterized with respect to how much, how fast,
when and where. Such quantitative data demands quantitative models. Thermodynamic …

Transcription activation by Escherichia coli catabolite activator protein (CAP) at each of two
classes of simple CAP-dependent promoters is understood in structural and mechanistic …

We have generated a series of variable-strength, constitutive, bacterial promoters that act
predictably in different sequence contexts, span two orders of magnitude in strength and …

Abstract The Crp-Fnr regulators, named after the first two identified members, are DNA-
binding proteins which predominantly function as positive transcription factors, though roles …

Bacteria commonly utilise a unique type of transporter, called Feo, to specifically acquire the
ferrous (Fe 2+) form of iron from their environment. Enterobacterial Feo systems are …

Bacteria use a variety of mechanisms to direct RNA polymerase to specific promoters in
order to activate transcription in response to growth signals or environmental cues …

The Escherichia coli cyclic AMP receptor protein (CRP) is a global regulator that controls
transcription initiation from more than 100 promoters by binding to a specific DNA sequence …

With the increasing amount of experimental data on gene expression and regulation, there
is a growing need for quantitative models to describe the data and relate them to their …

The Epstein-Barr virus (EBV) transactivator protein, termed Epstein-Barr virus nuclear
antigen 2 (EBNA2), plays a critical role in the regulation of latent viral transcription and in the …