[HTML][HTML] Major advances associated with the biosynthesis of milk

DE Bauman, IH Mather, RJ Wall, AL Lock - Journal of dairy science, 2006 - Elsevier
The mammary gland has an incredible level of organization and a remarkable ability to
convert circulating nutrients into milk components. This review highlights four areas of high …

[HTML][HTML] Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders

RJ Playford, CE Macdonald, WS Johnson - The American Journal of …, 2000 - Elsevier
Colostrum is the specific first diet of mammalian neonates and is rich in immunoglobulins,
antimicrobial peptides, and growth factors. In this article we review some of these …

[BOOK][B] Sentience and animal welfare

DM Broom - 2014 - books.google.com
Sentience–the ability to feel, perceive and experience–is central to the animal welfare
debate as it raises the question of whether animals experience suffering in life and death …

High level expression of active human alpha-1-antitrypsin in the milk of transgenic sheep

G Wright, A Carver, D Cottom, D Reeves, A Scott… - Bio/technology, 1991 - nature.com
We describe the generation of five sheep transgenic for a fusion of the ovine β-lactoglobulin
gene promoter to the human α1-antitrypsin (hα1AT) genomic sequences. Four of these …

Cloned transgenic cattle produce milk with higher levels of β-casein and κ-casein

B Brophy, G Smolenski, T Wheeler, D Wells… - Nature …, 2003 - nature.com
To enhance milk composition and milk processing efficiency by increasing the casein
concentration in milk, we have introduced additional copies of the genes encoding bovine β …

Genetic engineering of livestock

VG Pursel, CA Pinkert, KF Miller, DJ Bolt, RG Campbell… - Science, 1989 - science.org
Genetic engineering of livestock is expected to have a major effect on the agricultural
industry. However, accurate assessment of the consequences of transgene expression is …

Production of heterologous proteins in plants: strategies for optimal expression

PN Desai, N Shrivastava, H Padh - Biotechnology advances, 2010 - Elsevier
Plants are a promising expression system for the production of heterologous proteins,
especially therapeutic proteins. Currently the majority of therapeutic proteins are produced …

Long-term intravenous treatment of Pompe disease with recombinant human α-glucosidase from milk

JMP Van den Hout, JHJ Kamphoven, LPF Winkel… - …, 2004 - publications.aap.org
Objective. Recent reports warn that the worldwide cell culture capacity is insufficient to fulfill
the increasing demand for human protein drugs. Production in milk of transgenic animals is …

Transgenic bovine

HA DeBoer, R Strijker, HL Heyneker… - US Patent …, 1998 - Google Patents
A transgenic bovine is disclosed whose somatic and germ cells contain a transgene,
wherein the transgene comprising a mammary gland specific promoter, a mammary gland …

Generation Of Transgenic Dairy Cattle Using 'in vitro' Embryo Production

P Krimpenfort, A Rademakers, W Eyestone… - Bio/technology, 1991 - nature.com
We have combined gene transfer, by microinjection, with 'in vitro'embryo production
technology, enabling us to carry out non-surgical transfer, to recipient cows, of microinjected …