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PLGA-based implants for sustained delivery of peptides/proteins: Current status, challenge and perspectives
Peptide and protein drugs with therapeutic effects suffer from their short half-life and low
stability, albeit their high efficiency and specificity. To overcome these demerits, long-acting …
stability, albeit their high efficiency and specificity. To overcome these demerits, long-acting …
Engineering biomimetic biosensor using dual‐targeting multivalent aptamer regulated 3D DNA walker enables high‐performance detection of heterogeneous …
The phenotypic heterogeneity of circulating tumor cells (CTCs) and the nonspecific
adsorption of background cells impede the effective and sensitive detection of rare CTCs …
adsorption of background cells impede the effective and sensitive detection of rare CTCs …
Hybrid biointerface engineering nanoplatform for dual-targeted tumor hypoxia relief and enhanced photodynamic therapy
The clinical application of photodynamic therapy (PDT) is limited by the lack of tumor
selectivity of photosensitizer (PS) and the hypoxic tumor microenvironment (TME). To …
selectivity of photosensitizer (PS) and the hypoxic tumor microenvironment (TME). To …
Rationally remodeled biomimetic aptasensor enhances the detection performance of heterogeneous circulating tumor cells
Cell membrane biomimetic aptasensors stand out as a highly promising approach for
detecting heterogeneous circulating tumor cells (CTCs) thanks to the integration of the …
detecting heterogeneous circulating tumor cells (CTCs) thanks to the integration of the …
Erythrocyte Membrane-Camouflaged Hemin-Based Nanoplatform for Radiotherapy of Glioblastoma
B Yang, X Jiang, Y Liu, G Zheng, Y Li… - ACS Applied Nano …, 2024 - ACS Publications
Glioblastoma, accounting for 44% of all malignant brain tumors, is characterized by a dismal
prognosis due to high mortality, recurrence, and limited survival time. Current standard …
prognosis due to high mortality, recurrence, and limited survival time. Current standard …
A detailed evaluation of the advantages among extracellular vesicles from three cell origins for targeting delivery of celastrol and treatment of glioblastoma
X Zhang, Z Long, Z Qin, H Ran, S Wu, M Gong… - International Journal of …, 2024 - Elsevier
As one of the most common brain tumors, glioblastoma (GBM) lacks efficient therapeutic
treatment and remains lethal. Extracellular vesicles (EVs) have emerged as a promising …
treatment and remains lethal. Extracellular vesicles (EVs) have emerged as a promising …