Effects of silicon compounds on biomineralization, osteogenesis, and hard tissue formation

W Götz, E Tobiasch, S Witzleben, M Schulze - Pharmaceutics, 2019 - mdpi.com
Bioinspired stem cell-based hard tissue engineering includes numerous aspects: The
synthesis and fabrication of appropriate scaffold materials, their analytical characterization …

The essentials of marine biotechnology

A Rotter, M Barbier, F Bertoni, AM Bones… - Frontiers In marine …, 2021 - frontiersin.org
Coastal countries have traditionally relied on the existing marine resources (eg, fishing,
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …

Prospects and hazards of silica nanoparticles: Biological impacts and implicated mechanisms

R Ding, Y Li, Y Yu, Z Sun, J Duan - Biotechnology Advances, 2023 - Elsevier
With the thrive of nanotechnology, silica nanoparticles (SiNPs) have been extensively
adopted in the agriculture, food, cosmetic, and even biomedical industries. Due to the mass …

Calcium phosphate nanoparticles in biomineralization and biomaterials

Y Cai, R Tang - Journal of Materials Chemistry, 2008 - pubs.rsc.org
Recent developments in biomineralization and biomaterials have demonstrated that nano-
calcium phosphate particles play an important role in the formation of hard tissues in nature …

Natural marine sponges for bone tissue engineering: The state of art and future perspectives

RN Granito, MR Custódio… - Journal of Biomedical …, 2017 - Wiley Online Library
Marine life and its rich biodiversity provide a plentiful resource of potential new products for
the society. Remarkably, marine organisms still remain a largely unexploited resource for …

Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca2+ level in osteoblasts (SaOS-2 cells) in vitro

WEG Müller, X Wang, B Diehl-Seifert, K Kropf… - Acta Biomaterialia, 2011 - Elsevier
Inorganic polymeric phosphate is a physiological polymer that accumulates in bone cells. In
the present study osteoblast-like SaOS-2 cells were exposed to this polymer, complexed in a …

The role of biosilica in the osteoprotegerin/RANKL ratio in human osteoblast-like cells

M Wiens, X Wang, HC Schröder, U Kolb… - Biomaterials, 2010 - Elsevier
Earlier studies have demonstrated that biosilica, synthesized by the enzyme silicatein,
induces hydroxyapatite formation in osteoblast-like SaOS-2 cells. Here we study the effect of …

Bioactive effects of silica nanoparticles on bone cells are size, surface, and composition dependent

SW Ha, M Viggeswarapu, MM Habib, GR Beck Jr - Acta biomaterialia, 2018 - Elsevier
Silica based nanoparticles have been demonstrated to have intrinsic biologic activity
towards the skeleton and to function by promoting the differentiation of bone forming …

Silicate modulates the cross‐talk between osteoblasts (SaOS‐2) and osteoclasts (RAW 264.7 cells): Inhibition of osteoclast growth and differentiation

HC Schröder, XH Wang, M Wiens… - Journal of cellular …, 2012 - Wiley Online Library
It has been shown that inorganic monomeric and polymeric silica/silicate, in the presence of
the biomineralization cocktail, increases the expression of osteoprotegerin (OPG) in …

Osteogenic potential of biosilica on human osteoblast-like (SaOS-2) cells

M Wiens, X Wang, U Schloßmacher… - Calcified tissue …, 2010 - Springer
Biosilica is a natural polymer, synthesized by the poriferan enzyme silicatein from
monomeric silicate substrates. Biosilica stimulates mineralizing activity and gene expression …