Mesenchymal stem/stromal cell senescence: hallmarks, mechanisms, and combating strategies
Z Weng, Y Wang, T Ouchi, H Liu, X Qiao… - Stem Cells …, 2022 - academic.oup.com
Aging is a multifaceted and complicated process, manifested by a decline of normal
physiological functions across tissues and organs, leading to overt frailty, mortality, and …
physiological functions across tissues and organs, leading to overt frailty, mortality, and …
Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing
Bone has well documented natural healing capacity that normally is sufficient to repair
fractures and other common injuries. However, the properties of bone change throughout …
fractures and other common injuries. However, the properties of bone change throughout …
Senescence in mesenchymal stem cells: functional alterations, molecular mechanisms, and rejuvenation strategies
J Liu, Y Ding, Z Liu, X Liang - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and
differentiation. There is increasing evidence of the therapeutic value of MSCs in various …
differentiation. There is increasing evidence of the therapeutic value of MSCs in various …
Senescence in human mesenchymal stem cells: functional changes and implications in stem cell-based therapy
V Turinetto, E Vitale, C Giachino - International journal of molecular …, 2016 - mdpi.com
Regenerative medicine is extensively interested in develo** cell therapies using
mesenchymal stem cells (MSCs), with applications to several aging-associated diseases …
mesenchymal stem cells (MSCs), with applications to several aging-associated diseases …
Autophagy in bone remodeling: a regulator of oxidative stress
C Zhu, S Shen, S Zhang, M Huang, L Zhang… - Frontiers in …, 2022 - frontiersin.org
Bone homeostasis involves bone formation and bone resorption, which are processes that
maintain skeletal health. Oxidative stress is an independent risk factor, causing the …
maintain skeletal health. Oxidative stress is an independent risk factor, causing the …
Biomaterials based strategies for skeletal muscle tissue engineering: existing technologies and future trends
Skeletal muscles have a robust capacity to regenerate, but under compromised conditions,
such as severe trauma, the loss of muscle functionality is inevitable. Research carried out in …
such as severe trauma, the loss of muscle functionality is inevitable. Research carried out in …
Mitochondrial dynamics: fission and fusion in fate determination of mesenchymal stem cells
L Ren, X Chen, X Chen, J Li, B Cheng… - Frontiers in cell and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are pivotal to tissue homeostasis, repair, and regeneration
due to their potential for self-renewal, multilineage differentiation, and immune modulation …
due to their potential for self-renewal, multilineage differentiation, and immune modulation …
Mitochondrial transfer and regulators of mesenchymal stromal cell function and therapeutic efficacy
Mesenchymal stromal cell (MSC) metabolism plays a crucial role in the surrounding
microenvironment in both normal physiology and pathological conditions. While MSCs …
microenvironment in both normal physiology and pathological conditions. While MSCs …
The role of mitochondria in osteogenic, adipogenic and chondrogenic differentiation of mesenchymal stem cells
Mesenchymal stem cells (MSCs) are progenitors of connective tissues, which have emerged
as important tools for tissue engineering due to their differentiation potential along various …
as important tools for tissue engineering due to their differentiation potential along various …
Age-related changes in bone marrow mesenchymal stromal cells: a potential impact on osteoporosis and osteoarthritis development
Aging at the cellular level is a complex process resulting from accumulation of various
damages leading to functional impairment and a reduced quality of life at the level of the …
damages leading to functional impairment and a reduced quality of life at the level of the …