A safe and effective rotavirus vaccine is urgently needed, particularly in develo**
countries. Critical to vaccine development and implementation is a knowledge base …

The development of rotavirus vaccines that are based on heterotypic or serotype-specific
immunity has prompted many countries to establish programs to assess the disease burden …

Group A rotavirus (Rotavirus A, RVA) is the main cause of acute dehydrating diarrhea in
humans and numerous animal species. RVA shows vast diversity and a variety of human …

Rotavirus is the most common cause of severe diarrhea worldwide. In develo** countries,
rotavirus may cause 600,000 to 870,000 deaths each year, accounting for an estimated 20 …

The successful development and implementation of rotavirus vaccines will have a significant
impact on rotavirus-induced gastroenteritis in children worldwide. However, this introduction …

One hundred rotavirus strains detected in children with acute diarrhea in Blantyre, Malawi,
between July 1997 and January 1998 were characterized for G (VP7) and P (VP4) types by …

Rotavirus gastroenteritis is the major cause of severe dehydrating diarrhea in children
worldwide. This study compares rotavirus diarrhea in 351 children in a community-based …

ABSTRACT We characterized 1,534 rotavirus (RV) strains collected in Bangladesh from
1992 to 1997 to assess temporal changes in G type and to study the most common G and P …

Rotaviruses are segmented double-stranded RNA viruses with a high frequency of gene
reassortment, and they are a leading cause of global diarrheal deaths in children less than 5 …

We recently established a rotavirus strain surveillance system in the United States to monitor
the prevalent G serotypes before and after the anticipated implementation of a vaccination …