[HTML][HTML] Existing and emerging technologies for point-of-care testing

A St John, CP Price - The Clinical Biochemist Reviews, 2014 - ncbi.nlm.nih.gov
The volume of point-of-care testing (PoCT) has steadily increased over the 40 or so years
since its widespread introduction. That growth is likely to continue, driven by changes in …

Commercialization of microfluidic point-of-care diagnostic devices

CD Chin, V Linder, SK Sia - Lab on a Chip, 2012 - pubs.rsc.org
A large part of the excitement behind microfluidics is in its potential for producing practical
devices, but surprisingly few lab-on-a-chip based technologies have been successfully …

Rapid molecular detection of tuberculosis and rifampin resistance

CC Boehme, P Nabeta, D Hillemann… - … England Journal of …, 2010 - Mass Medical Soc
Background Global control of tuberculosis is hampered by slow, insensitive diagnostic
methods, particularly for the detection of drug-resistant forms and in patients with human …

Point-of-care nucleic acid testing for infectious diseases

A Niemz, TM Ferguson, DS Boyle - Trends in biotechnology, 2011 - cell.com
Nucleic acid testing for infectious diseases at the point of care is beginning to enter clinical
practice in developed and develo** countries; especially for applications requiring fast …

HIV-associated opportunistic CNS infections: pathophysiology, diagnosis and treatment

LN Bowen, B Smith, D Reich, M Quezado… - Nature Reviews …, 2016 - nature.com
Nearly 30 years after the advent of antiretroviral therapy (ART), CNS opportunistic infections
remain a major cause of morbidity and mortality in HIV-positive individuals. Unknown HIV …

Rapid Detection of Mycobacterium tuberculosis and Rifampin Resistance by Use of On-Demand, Near-Patient Technology

D Helb, M Jones, E Story, C Boehme… - Journal of clinical …, 2010 - Am Soc Microbiol
Current nucleic acid amplification methods to detect Mycobacterium tuberculosis are
complex, labor-intensive, and technically challenging. We developed and performed the first …

Evaluation of the GeneXpert MTB/RIF assay for rapid diagnosis of tuberculosis and detection of rifampin resistance in pulmonary and extrapulmonary specimens

AN Zeka, S Tasbakan, C Cavusoglu - Journal of clinical …, 2011 - Am Soc Microbiol
Mycobacterium tuberculosis remains one of the most significant causes of death from an
infectious agent. The rapid diagnosis of tuberculosis and detection of rifampin (RIF) …

Rapid molecular detection of extrapulmonary tuberculosis by the automated GeneXpert MTB/RIF system

D Hillemann, S Rüsch-Gerdes… - Journal of clinical …, 2011 - Am Soc Microbiol
ABSTRACT In total, 521 nonrespiratory specimens (91 urine, 30 gastric aspirate, 245 tissue,
113 pleural fluid, 19 cerebrospinal fluid [CSF], and 23 stool specimens) submitted to the …

PCR technologies for point of care testing: progress and perspectives

S Petralia, S Conoci - ACS sensors, 2017 - ACS Publications
Since the Human Genome Project completed in 2000, the sequencing of the first genome,
massive progress has been made by medical science in the early diagnosis and …

Real-time PCR: revolutionizing detection and expression analysis of genes

SA Deepak, KR Kottapalli, R Rakwal, G Oros… - Current …, 2007 - ingentaconnect.com
Invention of polymerase chain reaction (PCR) technology by Kary Mullis in 1984 gave birth
to real-time PCR. Real-time PCR-detection and expression analysis of gene (s) in real-time …