[HTML][HTML] Resistor–capacitor modeling of the cell membrane: A multiphysics analysis

C Brosseau, E Sabri - Journal of Applied Physics, 2021 - pubs.aip.org
In this Tutorial, we provide a discussion of “What are cell membrane resistance (MR) and
capacitance (MC)?” and then give a number of examples to illustrate how cell membranes …

Cell membrane electroporation modeling: A multiphysics approach

E Goldberg, C Suárez, M Alfonso, J Marchese… - …, 2018 - Elsevier
Electroporation-based techniques, ie techniques based on the perturbation of the cell
membrane through the application of electric pulses, are widely used at present in medicine …

Histopathological and ultrastructural changes after electroporation in pig liver using parallel-plate electrodes and high-performance generator

B López-Alonso, A Hernáez, H Sarnago, A Naval… - Scientific Reports, 2019 - nature.com
Irreversible electroporation (IRE) has gained attention as a new non-thermal therapy for
ablation with important benefits in terms of homogeneous treatment and fast recovery. In this …

Methods for delivery of biphasic electrical pulses for non-thermal ablation

RV Davalos, PA Garcia, JH Rossmeisl… - US Patent …, 2022 - Google Patents
2019-10-01 Assigned to VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
reassignment VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. ASSIGNMENT OF …

Devices and methods for high frequency electroporation

IIRE Neal, PA Garcia, RV Davalos… - US Patent …, 2022 - Google Patents
2019-06-10 Assigned to VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
reassignment VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. ASSIGNMENT OF …

Device and methods for delivery of biphasic electrical pulses for non-thermal ablation

IIRE Neal, PA Garcia, RV Davalos… - US Patent …, 2024 - Google Patents
The present invention provides systems, methods, and devices for electroporation-based
therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the …

System and method for ablating a tissue site by electroporation with real-time pulse monitoring

IIR Neal - US Patent 12,114,911, 2024 - Google Patents
A medical system for ablating a tissue site by electroporation with real-time pulse monitoring
during an electroporation treatment procedure is provided. The treatment control module …

Treatment planning for immunotherapy based treatments using non-thermal ablation techniques

RV Davalos, NB White, N Dervisis, IC Allen - US Patent 11,311,329, 2022 - Google Patents
2019-05-30 Assigned to VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY
reassignment VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY …

Assessing the electro-deformation and electro-poration of biological cells using a three-dimensional finite element model

D Shamoon, J Dermol-Černe, L Rems… - Applied Physics …, 2019 - pubs.aip.org
In this Letter, we explore how cell electro-deformation and electro-poration are connected.
We build a time-domain model of layered concentric shells (a model of biological cells) …

Rapid impedance spectroscopy for monitoring tissue impedance, temperature, and treatment outcome during electroporation-based therapies

MF Lorenzo, SP Bhonsle, CB Arena… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
Objective: Electroporation-based therapies (EBTs) employ high voltage pulsed electric fields
(PEFs) to permeabilize tumor tissue; this results in changes in electrical properties …