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Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management
Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …
underlying stress adaptation of cancer cells in response to therapy-induced hostile …
Toxicology and pharmacology of synthetic organoselenium compounds: An update
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …
compounds and some naturally occurring organoselenium amino acids. The use of …
Mitochondrial function in hypoxic ischemic injury and influence of aging
PB Ham III, R Raju - Progress in neurobiology, 2017 - Elsevier
Mitochondria are a major target in hypoxic/ischemic injury. Mitochondrial impairment
increases with age leading to dysregulation of molecular pathways linked to mitochondria …
increases with age leading to dysregulation of molecular pathways linked to mitochondria …
Heat stroke-induced cerebral cortex nerve injury by mitochondrial dysfunction: a comprehensive multi-omics profiling analysis
In recent years, global warming has led to frequent instances of extremely high temperatures
during summer, arousing significant concern about the adverse effects of high temperature …
during summer, arousing significant concern about the adverse effects of high temperature …
Mitochondrial Modulators: The Defender
Mitochondria are widely considered the “power hub” of the cell because of their pivotal roles
in energy metabolism and oxidative phosphorylation. However, beyond the production of …
in energy metabolism and oxidative phosphorylation. However, beyond the production of …
[HTML][HTML] Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant …
Oxidative stress and mitochondrial dysfunction are critical events in neurodegenerative
diseases; therefore, molecules that increase cellular antioxidant defenses represent a future …
diseases; therefore, molecules that increase cellular antioxidant defenses represent a future …
[HTML][HTML] Brain energy metabolism in ischemic stroke: effects of smoking and diabetes
Proper regulation of energy metabolism in the brain is crucial for maintaining brain activity in
physiological and different pathophysiological conditions. Ischemic stroke has a complex …
physiological and different pathophysiological conditions. Ischemic stroke has a complex …
Guanosine protects against traumatic brain injury-induced functional impairments and neuronal loss by modulating excitotoxicity, mitochondrial dysfunction, and …
Traumatic brain injury (TBI) is one of the most common types of brain injuries that cause
death or persistent neurological disturbances in survivors. Most of the promising …
death or persistent neurological disturbances in survivors. Most of the promising …
[HTML][HTML] Diphenyl diselenide alleviates tert-butyl hydrogen peroxide-induced oxidative stress and lipopolysaccharide-induced inflammation in rat glomerular …
Hyperglycemia, oxidative stress, and inflammation play key roles in the onset and
development of diabetic complications such as diabetic nephropathy (DN). Diphenyl …
development of diabetic complications such as diabetic nephropathy (DN). Diphenyl …
Diphenyl diselenide abrogates chlorpyrifos-induced hypothalamic-pituitary-testicular axis impairment in rats
Exposure to pesticide chlorpyrifos (CPF) has been implicated in reproductive deficits in both
humans and animals. Diphenyl diselenide (DPDS) is an organoselenium compound widely …
humans and animals. Diphenyl diselenide (DPDS) is an organoselenium compound widely …