Tularaemia: clinical aspects in Europe

M Maurin, M Gyuranecz - The Lancet Infectious Diseases, 2016 - thelancet.com
Tularaemia is a zoonotic disease caused by Francisella tularensis, a Gram-negative,
facultative intracellular bacterium. Typically, human and animal infections are caused by F …

Cathepsins in bacteria-macrophage interaction: defenders or victims of circumstance?

L Szulc-Dąbrowska, M Bossowska-Nowicka… - Frontiers in cellular …, 2020 - frontiersin.org
Macrophages are the first encounters of invading bacteria and are responsible for engulfing
and digesting pathogens through phagocytosis leading to initiation of the innate …

Helicobacter pylori versus the Host: Remodeling of the Bacterial Outer Membrane Is Required for Survival in the Gastric Mucosa

TW Cullen, DK Giles, LN Wolf, C Ecobichon… - PLoS …, 2011 - journals.plos.org
Modification of bacterial surface structures, such as the lipid A portion of lipopolysaccharide
(LPS), is used by many pathogenic bacteria to help evade the host innate immune response …

[HTML][HTML] Dietary Curcuma longa enhances resistance against Eimeria maxima and Eimeria tenella infections in chickens

DK Kim, HS Lillehoj, SH Lee, SI Jang, EP Lillehoj… - Poultry Science, 2013 - Elsevier
The effects of dietary supplementation with an organic extract of Curcuma longa on systemic
and local immune responses to experimental Eimeria maxima and Eimeria tenella infections …

MiR-155 Induction by F. novicida but Not the Virulent F. tularensis Results in SHIP Down-Regulation and Enhanced Pro-Inflammatory Cytokine Response

TJ Cremer, DH Ravneberg, CD Clay, MG Piper-Hunter… - PloS one, 2009 - journals.plos.org
The intracellular Gram-negative bacterium Francisella tularensis causes the disease
tularemia and is known for its ability to subvert host immune responses. Previous work from …

Prison break: pathogens' strategies to egress from host cells

N Friedrich, M Hagedorn, D Soldati-Favre… - … and Molecular Biology …, 2012 - Am Soc Microbiol
SUMMARY A wide spectrum of pathogenic bacteria and protozoa has adapted to an
intracellular life-style, which presents several advantages, including accessibility to host cell …

Inositol polyphosphate phosphatases in human disease

S Hakim, MC Bertucci, SE Conduit, DL Vuong… - Phosphoinositides and …, 2012 - Springer
Phosphoinositide signalling molecules interact with a plethora of effector proteins to regulate
cell proliferation and survival, vesicular trafficking, metabolism, actin dynamics and many …

Francisella tularensis reveals a disparity between human and mouse NLRP3 inflammasome activation

MK Atianand, EB Duffy, A Shah, S Kar, M Malik… - Journal of Biological …, 2011 - ASBMB
Pathogen-triggered activation of the inflammasome complex leading to caspase-1 activation
and IL-1β production involves similar sensor proteins between mouse and human. However …

Mechanisms of microbial escape from phagocyte killing

LM Smith, RC May - Biochemical society transactions, 2013 - portlandpress.com
Phagocytosis and phagosome maturation are crucial processes in biology. Phagocytosis
and the subsequent digestion of phagocytosed particles occur across a huge diversity of …

Host Immunity and Francisella tularensis: A Review of Tularemia in Immunocompromised Patients

O Bahuaud, C Le Brun, A Lemaignen - Microorganisms, 2021 - mdpi.com
Tularemia, caused by the bacterium Francisella tularensis, is an infrequent zoonotic
infection, well known in immunocompetent (but poorly described in immunocompromised) …