Smoke and autoimmunity: The fire behind the disease

C Perricone, M Versini, D Ben-Ami, S Gertel… - Autoimmunity …, 2016 - Elsevier
The association between smoke habit and autoimmunity has been hypothesized a long time
ago. Smoke has been found to play a pathogenic role in certain autoimmune disease as it …

Environmental issues in thyroid diseases

SM Ferrari, P Fallahi, A Antonelli… - Frontiers in …, 2017 - frontiersin.org
Environmental factors are determinant for the appearance of autoimmune thyroid diseases
(AITD) in susceptible subjects. Increased iodine intake, selenium, and vitamin D deficiency …

The etiology of autoimmune thyroid disease: a story of genes and environment

Y Tomer, A Huber - Journal of autoimmunity, 2009 - Elsevier
Autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and Hashimoto's
thyroiditis (HT) are prevalent autoimmune diseases, affecting up to 5% of the general …

Clinical relevance of environmental factors in the pathogenesis of autoimmune thyroid disease

WM Wiersinga - Endocrinology and metabolism, 2016 - synapse.koreamed.org
Genetic factors contribute for about 70% to 80% and environmental factors for about 20% to
30% to the pathogenesis of autoimmune thyroid disease (AITD). Relatives of AITD patients …

The environment and autoimmune thyroid diseases

MF Prummel, T Strieder… - European Journal of …, 2004 - academic.oup.com
Genetic factors play an important role in the pathogenesis of autoimmune thyroid disease
(AITD) and it has been calculated that 80% of the susceptibility to develop Graves' disease is …

Influences of age, gender, smoking, and family history on autoimmune thyroid disease phenotype

N Manji, JD Carr-Smith, K Boelaert… - The Journal of …, 2006 - academic.oup.com
Context: Both genetic and environmental factors contribute to susceptibility to Graves'
disease (GD) and Hashimoto's thyroiditis (HT), as well as disease manifestations. Objective …

Autoimmune disease after alemtuzumab treatment for multiple sclerosis in a multicenter cohort

M Cossburn, AA Pace, J Jones, R Ali, G Ingram… - Neurology, 2011 - AAN Enterprises
Objective: To define the rate, timing, and clinical risk factors for the development of
autoimmune disease (AID) after alemtuzumab treatment for multiple sclerosis (MS) …

Bidirectional association between autoimmune disease and perinatal depression: a nationwide study with sibling comparison

E Bränn, Y Chen, H Song, KD László… - Molecular …, 2024 - nature.com
Although major depression, characterized by a pro-inflammatory profile, genetically overlap
with autoimmune disease (AD) and the perinatal period involve immune system adaptations …

Cigarette smoking and autoimmune disease: what can we learn from epidemiology?

KH Costenbader, EW Karlson - Lupus, 2006 - journals.sagepub.com
Cigarette smoking has been causally linked to the development of multiple autoimmune
diseases, including rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis …

Thyrotropin receptor–associated diseases: from adenomata to Graves disease

TF Davies, T Ando, RY Lin, Y Tomer… - The Journal of clinical …, 2005 - Am Soc Clin Investig
The thyroid-stimulating hormone receptor (TSHR) is a G protein–linked, 7–transmembrane
domain (7-TMD) receptor that undergoes complex posttranslational processing unique to …