Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …

Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Radiation therapy is a mainstay of cancer treatment but does not always lead to complete
tumor regression. Here we combine radiotherapy with blockade of the 'don't-eat-me'cell …

Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages
of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently …

Ferroptosis, a form of regulated cell death caused by lipid peroxidation, was recently
identified as a natural tumor suppression mechanism. Here, we show that ionizing radiation …

The use of catalase-like nanozymes in relieving tumor hypoxia has been a promising
strategy for adjuvant radiotherapy, yet their catalytic mechanism and toxic potential remain …

Advances in nanoparticle synthesis and engineering have produced nanoscale agents
affording both therapeutic and diagnostic functions that are often referred to by the …

Radiotherapy (RT) is used routinely as a standard treatment for more than 50% of patients
with malignant tumors. The abscopal effect induced by local RT, which is considered as a …

Radiation therapy can potentially induce immunogenic cell death, thereby priming anti-
tumor adaptive immune responses. However, radiation-induced systemic immune …

Ferroptosis, a form of regulated cell death triggered by lipid peroxidation, was recently
identified as an important mechanism in radiotherapy (RT)-mediated tumor suppression and …