Artificial intelligence and machine learning in precision and genomic medicine

S Quazi - Medical Oncology, 2022‏ - Springer
The advancement of precision medicine in medical care has led behind the conventional
symptom-driven treatment process by allowing early risk prediction of disease through …

Artificial intelligence with multi-functional machine learning platform development for better healthcare and precision medicine

Z Ahmed, K Mohamed, S Zeeshan, XQ Dong - Database, 2020‏ - academic.oup.com
Precision medicine is one of the recent and powerful developments in medical care, which
has the potential to improve the traditional symptom-driven practice of medicine, allowing …

Evaluation of clinical prediction models (part 1): from development to external validation

GS Collins, P Dhiman, J Ma, MM Schlussel, L Archer… - Bmj, 2024‏ - bmj.com
Evaluating the performance of a clinical prediction model is crucial to establish its predictive
accuracy in the populations and settings intended for use. In this article, the first in a three …

Polygenic risk scores: from research tools to clinical instruments

CM Lewis, E Vassos - Genome medicine, 2020‏ - Springer
Genome-wide association studies have shown unequivocally that common complex
disorders have a polygenic genetic architecture and have enabled researchers to identify …

Machine learning prediction in cardiovascular diseases: a meta-analysis

C Krittanawong, RD Riley, KIE Snell, J Ensor, DL Burke… - Statistics in …, 2019‏ - Wiley Online Library
When designing a study to develop a new prediction model with binary or time‐to‐event
outcomes, researchers should ensure their sample size is adequate in terms of the number …

Cardiovascular disease risk prediction using automated machine learning: A prospective study of 423,604 UK Biobank participants

AM Alaa, T Bolton, E Di Angelantonio, JHF Rudd… - PloS one, 2019‏ - journals.plos.org
Background Identifying people at risk of cardiovascular diseases (CVD) is a cornerstone of
preventative cardiology. Risk prediction models currently recommended by clinical …

Predictive accuracy of a polygenic risk score–enhanced prediction model vs a clinical risk score for coronary artery disease

J Elliott, B Bodinier, TA Bond, M Chadeau-Hyam… - Jama, 2020‏ - jamanetwork.com
Importance The incremental value of polygenic risk scores in addition to well-established
risk prediction models for coronary artery disease (CAD) is uncertain. Objective To examine …