Abstract Pyrido [2, 3‐d] pyrimidine, a fused hetero‐bicyclic nucleus containing pyridine and
pyrimidine rings has attained the momentary attention in the sphere of multicomponent …

Abstract Carbonic anhydrases (CAs, EC 4.2. 1.1) are zinc-containing metalloenzymes that
can accelerate the hydration rate of CO 2 into HCO 3 _. But natural CA is usually unstable in …

New coumaryl-thiazole derivatives with the acetamide moiety as a linker between the alkyl
chains and/or the heterocycle nucleus were synthesized and in vitro tested as …

To develop novel antimicrobial agents, and based on the biologically active heterocyclic
quinoline and thiazole substituted, a series of novel α-aminophosphonates (9a–h) and (10i …

In the present study, a series of novel pyrazole‐thiazole hybrids (4a‐l) were designed,
synthesized and assessed for their in vitro antimicrobial activity against both Gram‐positive …

New coumarin derivatives with the carbamate moiety were synthesized and their inhibitory
effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) were evaluated …

Develo** novel chemical entities via different reactions and mechanisms is one of the
hottest topics in drug development. The coumarin moiety displays good cell permeability …

The one-pot synthesis of 8-prenylcoumarins from 1, 1-dimethylallylated salicylaldehydes
and the stabilized ylide [(ethoxycarbonyl) methylene] triphenylphosphorane under …

Organic photocatalysis has garnered significant interest in the field of photochemistry
because of its ability to generate active radical species under mild conditions via energy or …

Herein, we reported a novel series of α-aminophosphonates derivatives (IV) a–m bearing an
important pharmacophore coumarylthiazole moiety. All the new compounds have been …