Meiotic recombination: mixing it up in plants

Y Wang, GP Copenhaver - Annual Review of Plant Biology, 2018 - annualreviews.org
Meiosis halves diploid chromosome numbers to haploid levels that are essential for sexual
reproduction in most eukaryotes. Meiotic recombination ensures the formation of bivalents …

Learning to tango with four (or more): the molecular basis of adaptation to polyploid meiosis

K Bomblies - Plant reproduction, 2023 - Springer
Polyploidy, which arises from genome duplication, has occurred throughout the history of
eukaryotes, though it is especially common in plants. The resulting increased size …

Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions

K Choi, X Zhao, AJ Tock, C Lambing… - Genome …, 2018 - genome.cshlp.org
Meiotic recombination initiates from DNA double-strand breaks (DSBs) generated by SPO11
topoisomerase-like complexes. Meiotic DSB frequency varies extensively along eukaryotic …

FANCM promotes class I interfering crossovers and suppresses class II non-interfering crossovers in wheat meiosis

SD Desjardins, J Simmonds, I Guterman… - Nature …, 2022 - nature.com
FANCM suppresses crossovers in plants by unwinding recombination intermediates. In
wheat, crossovers are skewed toward the chromosome ends, thus limiting generation of …

Chromosome-level assembly of Arabidopsis thaliana Ler reveals the extent of translocation and inversion polymorphisms

L Zapata, J Ding, EM Willing… - Proceedings of the …, 2016 - National Acad Sciences
Resequencing or reference-based assemblies reveal large parts of the small-scale
sequence variation. However, they typically fail to separate such local variation into colinear …

Epigenetic activation of meiotic recombination near Arabidopsis thaliana centromeres via loss of H3K9me2 and non-CG DNA methylation

CJ Underwood, K Choi, C Lambing, X Zhao… - Genome …, 2018 - genome.cshlp.org
Eukaryotic centromeres contain the kinetochore, which connects chromosomes to the
spindle allowing segregation. During meiosis, centromeres are suppressed for inter …

Unleashing meiotic crossovers in hybrid plants

JB Fernandes, M Séguéla-Arnaud… - Proceedings of the …, 2018 - National Acad Sciences
Meiotic crossovers shuffle parental genetic information, providing novel combinations of
alleles on which natural or artificial selection can act. However, crossover events are …

Natural variation and dosage of the HEI10 meiotic E3 ligase control Arabidopsis crossover recombination

PA Ziolkowski, CJ Underwood, C Lambing… - Genes & …, 2017 - genesdev.cshlp.org
During meiosis, homologous chromosomes undergo crossover recombination, which
creates genetic diversity and balances homolog segregation. Despite these critical …

The megabase-scale crossover landscape is largely independent of sequence divergence

Q Lian, V Solier, B Walkemeier, S Durand… - Nature …, 2022 - nature.com
Meiotic recombination frequency varies along chromosomes and strongly correlates with
sequence divergence. However, the causal relationship between recombination landscapes …

An Ultra High-Density Arabidopsis thaliana Crossover Map That Refines the Influences of Structural Variation and Epigenetic Features

BA Rowan, D Heavens, TR Feuerborn, AJ Tock… - Genetics, 2019 - academic.oup.com
Rowan et al. generated a dataset of over 17,000 meiotic crossovers (COs) from over 2000
F2 individuals from a single Arabidopsis thaliana cross. The unprecedented density of COs …