Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs

W Liu, R Gust - Chemical Society Reviews, 2013 - pubs.rsc.org
The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …

Silver coordination compounds: A new horizon in medicine

S Medici, M Peana, G Crisponi, VM Nurchi… - Coordination Chemistry …, 2016 - Elsevier
Silver coordination compounds with a number of different ligands (N-heterocyclic carbenes,
phosphines, N-heterocycles and others) possess several properties, ranging from …

The Medicinal applications of imidazolium carbene− metal complexes

KM Hindi, MJ Panzner, CA Tessier, CL Cannon… - Chemical …, 2009 - ACS Publications
Ofele and Wanzlick reported the synthesis of the first N-heterocyclic carbene (NHC)-metal
complexes in 1968. 1, 2 The isolation of the first free carbene by Arduengo in 1991 set the …

Recent advances in the medical use of silver complex

X Liang, S Luan, Z Yin, M He, C He, L Yin, Y Zou… - European Journal of …, 2018 - Elsevier
Silver has been used for numerous medical conditions for centuries, however, most of the
current clinical silver agents all have their own disadvantages limiting the clinical …

Anti-proliferative and anti-tumor activity of silver(i) compounds

CN Banti, SK Hadjikakou - Metallomics, 2013 - academic.oup.com
Silver is proving to have a number of medicinal applications; as an antiseptic, an
antibacterial, and an anti-inflammatory, while any biological role for it is currently unknown …

Substrate-Modulated Synthesis of Metal–Organic Hybrids by Tunable Multiple Aryl–Metal Bonds

Q Zhong, K Niu, L Chen, H Zhang… - Journal of the …, 2022 - ACS Publications
Assembly of semiconducting organic molecules with multiple aryl–metal covalent bonds into
stable one-and two-dimensional (1D and 2D) metal–organic frameworks represents a …

Metal-NHC complexes: a survey of anti-cancer properties

ML Teyssot, AS Jarrousse, M Manin, A Chevry… - Dalton …, 2009 - pubs.rsc.org
New weapons to fight cancer are constantly needed. Among chemotherapeutics, anti-cancer
metal-drugs have enjoyed a long and successful history since the discovery of the …

Recent advances in supramolecular design and assembly of silver (I) coordination polymers

CL Chen, BS Kang, CY Su - Australian journal of chemistry, 2006 - CSIRO Publishing
The supramolecular chemistry of Ag (i) coordination assemblies continues to attract attention
due to their versatile structural diversity and potential physical and chemical functions. This …

Novel benzyl-substituted N-heterocyclic carbene–silver acetate complexes: synthesis, cytotoxicity and antibacterial studies

S Patil, A Deally, B Gleeson, H Müller-Bunz… - Metallomics, 2011 - academic.oup.com
From the reaction of 1-methylimidazole (1a), 4, 5-dichloro-1 H-imidazole (1bII) and 1-
methylbenzimidazole (1c) with p-cyanobenzyl bromide (2a), non-symmetrically substituted N …

Anticancer activity of Ag (I) N‐heterocyclic carbene complexes derived from 4, 5‐Dichloro‐1H‐imidazole

DA Medvetz, KM Hindi, MJ Panzner, AJ Ditto… - Metal‐Based …, 2008 - Wiley Online Library
A class of Ag (I) N‐heterocyclic carbene silver complexes, 1–3, derived from 4, 5‐dichloro‐
1H‐imidazole has been evaluated for their anticancer activity against the human cancer cell …