In the 1970s, treatment with thyroid extract was superseded by levothyroxine, a synthetic l
form of tetraiodothyronine. Since then, no major innovation has emerged for the treatment of …

Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed.
Despite the basic tenets of initiating and adjusting levothyroxine being agreed on, there are …

Although levothyroxine is one of the most prescribed medications in the world, its
bioavailability has been reported to be impaired by many factors, including interfering drugs …

Levothyroxine (LT4) is effective for most patients with hypothyroidism. However, a minority of
the patients remain symptomatic despite the normalization of serum thyrotropin levels …

Levothyroxine monotherapy has been the standard of care for treatment of hypothyroidism
for more than 40 years. However, patients treated with levothyroxine have relatively lower …

Regardless of the cause, hypothyroidism should be treated with levothyroxine. The
objectives of management are the normalization of TSH levels and the relief of symptoms. In …

Daily levothyroxine (LT4) is the standard of care for the treatment of hypothyroidism;
however, a small number of patients experience residual symptoms of hypothyroidism …

Introduction Levothyroxine (LT4) at doses that maintain the serum thyroid-stimulating
hormone levels within the normal range constitutes the standard of care for the treatment of …

Approximately 10%–15% of subjects with hypothyroidism on L-thyroxine (LT4) alone have
persistent symptoms affecting their quality of life (QoL). Although the cause is unclear, there …

From my lens through serving the American Thyroid As-sociation (ATA) in several roles, I
have framed this opportunity to highlight select studies published between October 2021 …