The interplay between monosodium glutamate (MSG) consumption and metabolic disorders

OT Kayode, JA Bello, JA Oguntola, AAA Kayode… - Heliyon, 2023 - cell.com
Monosodium glutamate (MSG) is one of the most popular food additives in the world and is
often ingested with commercially processed foods. It can be described as a sodium salt of …

Exploring Nrf2 as a therapeutic target in testicular dysfunction

DE Rotimi, OA Ojo, TD Olaolu, OS Adeyemi - Cell and Tissue Research, 2022 - Springer
Testicular dysfunction, a major contributory factor to infertility, has received a lot of attention
over the recent years. Several studies have linked abnormal sperm function and morphology …

Therapeutic potential of rutin in male infertility: a mini review

DE Rotimi, TC Elebiyo, OA Ojo - Journal of Integrative Medicine, 2023 - Elsevier
Male infertility has become a problem worldwide, and recent research has emphasized the
development of more effective therapy options. Among natural compounds, rutin has been …

Oxidative stress-induced hormonal disruption in male reproduction

DE Rotimi, MA Acho, BM Falana, TD Olaolu… - Reproductive …, 2024 - Springer
Research into the impacts of oxidative stress (OS), and hormonal balance on reproductive
potential has increased over the last 40 years possibly due to rising male infertility …

Glutamate-A multifaceted molecule: Endogenous neurotransmitter, controversial food additive, design compound for anti-cancer drugs. A critical appraisal

OL Moldovan, A Rusu, C Tanase, CE Vari - Food and Chemical Toxicology, 2021 - Elsevier
One of the most widely used flavour enhancers in the food industry is monosodium
glutamate (MSG). MSG consumption has been on an upward trend, worrying in terms of …

Pharmacological action of quercetin against testicular dysfunction: A mini review

DE Rotimi, TD Olaolu, OS Adeyemi - Journal of Integrative Medicine, 2022 - Elsevier
The testis is an immune-privileged organ susceptible to oxidative stress and inflammation,
two major factors implicated in male infertility. A reduction in the concentration and activities …

Interaction between apoptosis and autophagy in testicular function

DE Rotimi, SK Singh - Andrologia, 2022 - Wiley Online Library
Several processes including oxidative stress, apoptosis, inflammation and autophagy are
related to testicular function. Recent studies indicate that a crosstalk between apoptosis and …

Atrazine exposure caused oxidative stress in male rats and inhibited brain‐pituitary‐testicular functions

DE Rotimi, OA Ojo, OS Adeyemi - Journal of Biochemical and …, 2024 - Wiley Online Library
Exposure to the herbicide atrazine has been shown to have deleterious effects on human
and animal reproduction. To determine whether atrazine influences the brain‐pituitary …

Monosodium glutamate intake and risk assessment in China nationwide, and a comparative analysis worldwide

H Yu, R Wang, Y Zhao, Y Song, H Sui, Y Wu, H Miao… - Nutrients, 2023 - mdpi.com
The sixth Total Diet Study (TDS) of China included a countrywide study to assess the health
effects of MSG (monosodium glutamate). MSG detection, consumption analysis, and risk …

Energy metabolism and spermatogenesis

DE Rotimi, M Iyobhebhe, ET Oluwayemi, OP Olajide… - Heliyon, 2024 - cell.com
Infertility has become a significant health burden around the globe as it is believed that 15%
of married couples struggle with infertility, with half of the problem accrued to the male. The …